Evidence map›Paper›PMID 33070712›Full record

ArticleStroke2020

Mechanical Thrombectomy in Medium Vessel Occlusions: Blind Exchange With Mini-Pinning Technique Versus Mini Stent Retriever Alone.

Carlos Pérez-García, Manuel Moreu, Santiago Rosati, Patricia Simal, Jose Antonio Egido, Carlos Gomez-Escalonilla, Juan Arrazola

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05983757 (A Phase III, Randomized, Multicenter, Investigational, Open Label Clinical Trial That Will Examine Whether Treatment With Endovascular Thrombectomy is Superior to Standard Medical Therapy Alone in Patients Who Suffer a Distal Medium Vessel Occlusion Ischemic Strokes.), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05983757 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Phase III, Randomized, Multicenter, Investigational, Open Label Clinical Trial That Will Examine Whether Treatment With Endovascular Thrombectomy is Superior to Standard Medical Therapy Alone in Patients Who Suffer a Distal Medium Vessel Occlusion Ischemic Strokes.

TypeinterventionalSponsorRaul NogueiraRan2024 to 2027Enrolled584ConditionsIschemic StrokeArmsExperimental: endovascular thrombectomy in patients who suffer a distal medium vessel occlusion, Standard medical management
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Comparing Tigertriever 13 to other thrombectomy devices for distal medium vessel occlusion: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. A review of acute ischemic stroke caused by distal, medium vessel occlusions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Three-dimensional rotational angiography improves mechanical thrombectomy recanalization rate for acute ischaemic stroke due to middle cerebral artery M2 segment occlusions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  11. Article
  12. Article
  13. Multicenter investigation of technical and clinical outcomes after thrombectomy for Proximal Medium Vessel Occlusion (pMeVO) by frontline technique.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carlos Pérez-GarcíaDepartment of Interventional Neuroradiology (C.P.-G., M.M., S.R.), Hospital Clínico San Carlos, Madrid, Spain.
Manuel MoreuDepartment of Interventional Neuroradiology (C.P.-G., M.M., S.R.), Hospital Clínico San Carlos, Madrid, Spain.
Santiago RosatiDepartment of Interventional Neuroradiology (C.P.-G., M.M., S.R.), Hospital Clínico San Carlos, Madrid, Spain.
Patricia SimalDepartment of Neurology (P.S., J.A.E., C.G.-E.), Hospital Clínico San Carlos, Madrid, Spain.
Jose Antonio EgidoDepartment of Neurology (P.S., J.A.E., C.G.-E.), Hospital Clínico San Carlos, Madrid, Spain.
Carlos Gomez-EscalonillaDepartment of Neurology (P.S., J.A.E., C.G.-E.), Hospital Clínico San Carlos, Madrid, Spain.
Juan ArrazolaDepartment of Radiology (J.A.), Hospital Clínico San Carlos, Madrid, Spain.
Hospital Clínico San Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMechanical thrombectomy techniques for intracranial medium vessel occlusions (MeVOs) have evolved in recent years, although the optimal approach is still unclear. The aim of this study was to investigate the effectiveness and safety of mechanical thrombectomy in MeVOs using mini (0.017 inches microcatheter compatible) stent retrievers combined with low-profile (0.035 inches distal inner diameter) distal aspiration catheters through the blind exchange/mini-pinning (BEMP) technique compared with mini stent retrievers alone.

methodsRetrospective review of a prospectively maintained database of patients treated with the BEMP technique or mini stent retriever alone for intracranial MeVOs from 2017 to 2020 in a comprehensive stroke center. Both groups were compared about baseline characteristics, occlusion site, clinical presentation, clot cause, procedural outcomes (MeVO first-pass and final expanded Thrombolysis in Cerebral Ischemia score, the mini stent retriever used, number of passes with the front-line approach, and need of rescue therapy), safety outcomes (emboli to unwanted territories and hemorrhagic complications), and clinical outcomes at 90 days. Multivariable logistic regression analysis was performed with potential predictors of vessel recanalization to find independent variables associated with MeVO first-pass expanded Thrombolysis in Cerebral Ischemia 2c/3 recanalization.

resultsWe reviewed 102 patients/106 MeVOs treated with the BEMP technique (n=56) or mini stent retriever (n=50). There was a higher rate of MeVO first-pass expanded Thrombolysis in Cerebral Ischemia 2c/3 recanalization (57% versus 34%,

conclusionsIn the setting of MeVOs, the BEMP technique may lead to higher rates of the first-pass recanalization and a lower incidence of symptomatic intracranial hemorrhage than mini stent retrievers alone.

Indexed as

AgedAged, 80 and overFemaleHumansInfarction, Anterior Cerebral ArteryInfarction, Middle Cerebral ArteryInfarction, Posterior Cerebral ArteryIntracranial HemorrhagesIschemic StrokeLogistic ModelsMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsRetrospective StudiesThrombectomycathetersincidenceintracranial hemorrhagesstentsthrombectomy

Identifiers

PMID33070712
OpenAlexW3092933495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.