ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021
Leiomyosarcoma in a cervical myelomeningocele: a rare complication in a neglected case.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Congenital lumbosacral meningocele with malignant transformation to epithelioid angiosarcoma: A case report of complex spinal anomalies.Radiology case reports · 2026Article
- Neglected cervical meningocele in an adult: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
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5 authors at 1 institution in 1 country.
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Abstract
background and importanceAsymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin. CLINICAL PRESENTATION: The authors report a case of an 18-year-old male patient who developed leiomyosarcoma within chronically neglected cervical myelomeningocele.
conclusionA non-healing ulcer of any aetiology is a bed for carcinogenesis. Neglected myelomeningoceles, for any reason, may convert a benign entity to a malignant pathology. To our best knowledge, this is the first case of a leiomyosarcoma arising de novo from myelomeningocele.
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