Evidence map›Paper›PMID 33070043›Full record

ArticleJournal of psychosomatic research2020

Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study.

Brett D Thombs, Linda Kwakkenbos, Richard S Henry, Marie-Eve Carrier, Scott Patten, Sami Harb, Angelica Bourgeault, Lydia Tao, Susan J Bartlett, Luc Mouthon and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of psychosomatic research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  15. Functional and psychosocial impact of COVID-19 pandemic on rheumatic patients' quality of life in Saudi Arabia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 20 institutions in 8 countries.

Brett D ThombsLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, Quebec H3A 1A2, Canada; Department of Medicine, McGill University, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada; Department of Psychology, McGill University, 2001 McGill College Avenue, Montreal, Quebec H3A 1G1, Canada; Department of Educational and Counselling Psychology, McGill University, 3700 McTavish Street, Montreal, Quebec H3A 1Y2, Canada; Biomedical Ethics Unit, McGill University, 3647 Peel Street, Montreal, Quebec H3A 1X1, Canada. Electronic address: brett.thombs@mcgill.ca.
Linda KwakkenbosDepartment of Clinical Psychology, Behavioural Science Institute, Radboud University, Montessorilaan 3, 6525 HR, Nijmegen, the Netherlands.
Richard S HenryLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada.
Marie-Eve CarrierLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada.
Scott PattenDepartment of Community Health Sciences, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada; Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada; O'Brien Institute for Public Health, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada.
Sami HarbLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada.
Angelica BourgeaultLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada.
Lydia TaoLady Davis Institute for Medical Research, Jewish General Hospital, 4333 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1E4, Canada.
Susan J BartlettDepartment of Medicine, McGill University, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada; Research Institute of the McGill University Health Centre, Centre for Outcomes Research and Evaluation, 5252 de Maisonneuve #3D.57, Montreal, Quebec H4A 2S5, Canada.
Luc MouthonUniversité Paris Descartes, Assistance Publique-Hôpitaux de Paris, 3 Avenue Victoria, 75004 Paris, France; Service de Médecine Interne, Centre de Reference Maladies Systémiques Autoimmunes Rares d'Ile de France, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France.
John VargaNorthwestern Scleroderma Program, Feinberg School of Medicine, Northwestern University, 675 North St. Clair, Chicago, IL 60611, USA.
Andrea BenedettiDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, Quebec H3A 1A2, Canada; Department of Medicine, McGill University, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada; Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, 5252 boulevard de Maisonneuve, Montreal, Quebec H4A 3S5, Canada.
SPIN Patient Advisors
SPIN Investigators
The University of Texas MD Anderson Cancer Center · USUniversité de Sherbrooke · CAJewish General Hospital · CADélégation Paris 5 · FRHôpital Cochin · FRMcGill University Health Centre · CASalford Royal NHS Foundation Trust · GBHospital for Special Surgery · USMultiple Sclerosis Society of Canada · CANorthwestern University · USUniversity of Pittsburgh · USCentre Hospitalier de l’Université de Montréal · CACentre Hospitalier Universitaire de Nantes · FRMcGill University · CAMcMaster University · CAMount Sinai Hospital · CARadboud University Nijmegen · NLSan Diego State University · USScleroderma and Raynaud's UK · GBScleroderma Foundation · US

Funding

Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
NCATS NIH HHS KL2 TR003168
6 · The paper itself

Abstract

introductionNo studies have reported mental health symptom comparisons prior to and during COVID-19 in vulnerable medical populations.

objectiveTo compare anxiety and depression symptoms among people with a pre-existing medical condition and factors associated with changes.

methodsPre-COVID-19 Scleroderma Patient-centered Intervention Network Cohort data were linked to COVID-19 data from April 2020. Multiple linear and logistic regression were used to assess factors associated with continuous change and ≥ 1 minimal clinically important difference (MCID) change for anxiety (PROMIS Anxiety 4a v1.0; MCID = 4.0) and depression (Patient Health Questionnaire-8; MCID = 3.0) symptoms, controlling for pre-COVID-19 levels.

resultsMean anxiety symptoms increased 4.9 points (95% confidence interval [CI] 4.0 to 5.7). Depression symptom change was negligible (0.3 points; 95% CI -0.7 to 0.2). Compared to France (N = 159), adjusted anxiety symptom change scores were significantly higher in the United Kingdom (N = 50; 3.3 points, 95% CI 0.9 to 5.6), United States (N = 128; 2.5 points, 95% CI 0.7 to 4.2), and Canada (N = 98; 1.9 points, 95% CI 0.1 to 3.8). Odds of ≥1 MCID increase were 2.6 for the United Kingdom (95% CI 1.2 to 5.7) but not significant for the United States (1.6, 95% CI 0.9 to 2.9) or Canada (1.4, 95% CI 0.7 to 2.5). Older age and adequate financial resources were associated with less continuous anxiety increase. Employment and shorter time since diagnosis were associated with lower odds of a ≥ 1 MCID increase.

conclusionsAnxiety symptoms, but not depression symptoms, increased dramatically during COVID-19 among people with a pre-existing medical condition.

Indexed as

AdultAgedCanadaCohort StudiesCOVID-19FemaleFranceHumansLongitudinal StudiesMaleMental DisordersMental HealthMiddle AgedPatient-Centered CareScleroderma, SystemicUnited KingdomAdultAnxietyClinical epidemiologyCOVID-19Depressed moodDepressive symptomsEpidemiologyPandemicSclerodermaSystemic sclerosis

Identifiers

PMID33070043
PMCPMC7532799
OpenAlexW3091595695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.