Evidence map›Paper›PMID 33069880›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2021

Provider Attitudes and Practices for Alcohol Screening, Treatment, and Education in Patients With Liver Disease: A Survey From the American Association for the Study of Liver Diseases Alcohol-Associated Liver Disease Special Interest Group.

Gene Y Im, Jessica L Mellinger, Adam Winters, Elizabeth S Aby, Zurabi Lominadze, John Rice, Michael R Lucey, Juan P Arab, Aparna Goel, Loretta L Jophlin and 9 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06471686 (Safety of Acamprosate in Treating Alcohol Use Disorder in the Post Liver Transplant Populations), which is not on this map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06471686 phase2completednot on this map

Safety of Acamprosate in Treating Alcohol Use Disorder in the Post Liver Transplant Populations

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2023Enrolled30ConditionsAlcohol Use Disorder, Liver Transplant, ComplicationsArmsAcamprosate
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Training hepatologists in alcohol use disorder management: a pilot study.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026
    Article
  5. Addressing Alcohol Use Disorder in Alcohol-Associated Liver Disease.Clinical and translational gastroenterology · 2026
    Review
  6. Role of social determinants and outcomes of patients with alcohol-associated liver disease referred for early liver transplantation: A multicenter analysis.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
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  10. Observational
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  19. Article
  20. Alcohol-related liver disease.Gastroenterology report · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 17 institutions in 4 countries.

Gene Y ImDivision of Liver Diseases, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: gene.im@mountsinai.org.
Jessica L MellingerDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan.
Adam WintersVatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California.
Elizabeth S AbyDivision of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, Minnesota.
Zurabi LominadzeDivision of Gastroenterology, Department of Medicine, University of Maryland, Baltimore, Maryland.
John RiceDivision of Gastroenterology and Hepatology, University of Wisconsin School of Medicine, Madison, Wisconsin.
Michael R LuceyDivision of Gastroenterology and Hepatology, University of Wisconsin School of Medicine, Madison, Wisconsin.
Juan P ArabDepartamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Aparna GoelDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California.
Loretta L JophlinDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Courtney B ShermanDivision of Gastroenterology and Hepatology, University of California, San Francisco, San Francisco, California.
Richard ParkerLeeds Liver Unit, St James's University Hospital, Leeds, United Kingdom.
Po-Hung ChenDepartment of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Deepika DevuniDivision of Gastroenterology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Sandeep SidhuDepartment of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Winston DunnDepartment of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas.
Gyongyi SzaboDivision of Gastroenterology and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Ashwani K SingalDivision of Gastroenterology and Hepatology, Department of Medicine, Avera McKennan University Hospital Transplant Institute, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Vijay H ShahDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USUniversity of Wisconsin–Madison · USDayanand Medical College & Hospital · INHarvard University · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins Medicine · USPontificia Universidad Católica de Chile · CLStanford University · USSt James's University Hospital · GBUniversity of California, Los Angeles · USUniversity of California, San Francisco · USUniversity of Kansas Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Massachusetts Chan Medical School · USUniversity of Michigan–Ann Arbor · USUniversity of Minnesota · USUniversity of South Dakota · US

Funding

Candidate Selection for Liver Transplantation in Patients with Alcohol-related Liver DiseaseK23AA028297 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHEN, PO-HUNG (VICTOR) · 2020 to 2024
$991k
NIAAA NIH HHS K23 AA028297
6 · The paper itself

Abstract

BACKGROUND &

aimsWhile abstinence-promoting behavioral and pharmacotherapies are part of the therapeutic foundation for alcohol use disorder (AUD) and alcohol-associated liver disease (ALD), these therapies, along with alcohol screening and education, are often underutilized. Our aim was to examine provider attitudes and practices for alcohol screening, treatment and education in patients with liver disease.

methodsWe conducted a survey of primarily (89%) hepatology and gastroenterology providers within (80%) and outside the United States (20%). Surveys were sent to 921 providers with 408 complete responses (44%), of whom 343 (80%) work in a tertiary liver transplant center.

resultsWhile alcohol screening rates in liver disease patients was nearly universal, less than half of providers reported practicing with integrated addiction providers, using alcohol biomarkers and screening tools. Safe alcohol use by liver disease patients was felt to exist by 40% of providers. While 60% of providers reported referring AUD patients for behavioral therapy, 71% never prescribed AUD pharmacotherapy due to low comfort (84%). Most providers (77%) reported low addiction education and 90% desired more during GI/hepatology fellowship training. Amongst prescribers, baclofen was preferred, but with gaps in pharmacotherapy knowledge. Overall, there was low adherence to the 2019 AASLD practice guidance for ALD, although higher in hepatologists and experienced providers.

conclusionsWhile our survey of hepatology and gastroenterology providers demonstrated higher rates of alcohol screening and referrals for behavioral therapy, we found low rates of prescribing AUD pharmacotherapy due to knowledge gaps from insufficient education. Further studies are needed to assess interventions to improve provider alignment with best practices for treating patients with AUD and ALD.

Indexed as

AlcoholismLiver DiseasesAttitudeHumansPublic OpinionSurveys and QuestionnairesUnited StatesAddiction MedicineAlcohol-Associated Liver DiseaseAlcohol PharmacotherapyAlcohol SurveyAlcohol Use Disorder

Identifiers

PMID33069880
PMCPMC8291372
OpenAlexW3093231899

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.