SynthesisPediatric research2021
Social determinants of health and outcomes for children and adults with congenital heart disease: a systematic review.
Synthesis in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preoperative nutrition status in children with congenital heart disease and its impact on postoperative outcomes: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Parent-reported quality of life at school age among children born extremely preterm is associated with non-medical determinants of health and developmental outcomes.Early human development · 2026Article
- Computer-Based Simulation Technologies in Pediatric Cardiovascular Diseases: A Systematic Review of Applications and Outcomes.Healthcare (Basel, Switzerland) · 2026Review
- Clinical characteristics and healthcare utilization of adults with congenital heart disease on Medicaid insurance in the United States.International journal of cardiology. Congenital heart disease · 2026Article
- Socioeconomic Factors Associated with Fetal Tachyarrhythmia Management and Outcomes: A Single-Center Retrospective Review of a Consistent Protocol.Pediatric cardiology · 2026Article
- Outcomes of Congenital Heart Disease Deliveries at a Freestanding Children's Hospital.Pediatric cardiology · 2026Article
- Geographical inequity in out-of-pocket costs for families of children with congenital heart disease requiring neurodevelopment support: an examination of policy scenarios using economic modelling.International journal for equity in health · 2026Article
- Neonatal pre-discharge heart rate variability and neurodevelopmental outcomes at 1- and 5-years in children with transposition of the great arteries.Pediatric research · 2026Article
- Fetal Cardiology Prenatal Care Quality and Social Determinants of Health in Critical Congenital Heart Disease.Pediatric cardiology · 2026Article
- Assessment of Early Development in Congenital Heart Disease Using a Novel Caregiver Rating Method.Pediatric cardiology · 2026Article
- Postoperative complications after paediatric cardiac surgery: the role of ethnicity and deprivation - a national cohort study.Archives of disease in childhood · 2026Article
- An Examination of Social Determinants of Health and their Association with Preventable and Urgent Readmissions in Pediatric Acute Care Cardiology.Pediatric cardiology · 2026Article
- Individual Risk Versus Population Incidence: A Case Example With Congenital Heart Defects.Academic pediatrics · 2026Article
- Global burden of developmental intellectual disability in children and adolescents with congenital heart disease, 1990-2021: a population-based study.Translational pediatrics · 2026Article
- Genetics and Brain Health in Adults With Congenital Heart Disease: A Consensus Statement From the ACHD/Neuro 2024 Conference.Journal of the American Heart Association · 2026Article
- Prioritizing Neurocognitive and Psychosocial Outcomes in Adults With Congenital Heart Disease: A Consensus Statement From the Adults With Congenital Heart Disease/Neuro 2024 Conference.Journal of the American Heart Association · 2026Article
- Mortality amongst European children with congenital anomalies: Associations with socio-economic status in the EUROLINKCAT cohort.PloS one · 2026Observational
- Characterizing neurodevelopmental follow-up attendance of children with congenital heart disease.Pediatric research · 2026Article
- Never enough: bridging the gap between evidence and facts in the neurodevelopmental assessment of congenital heart disease children.Pediatric research · 2026Article
- Rethinking cardiac neurodevelopment: a dimensional model of adversity in congenital heart disease.Frontiers in pediatrics · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSocial determinants of health (SDH) can substantially impact health outcomes. A systematic review, however, has never been conducted on associations of SDH with congenital heart disease (CHD) outcomes. The aim, therefore, was to conduct such a systematic review.
methodsSeven databases were searched through May 2020 to identify articles on SDH associations with CHD. SDH examined included poverty, uninsurance, housing instability, parental educational attainment, immigration status, food insecurity, and transportation barriers. Studies were independently selected and coded by two researchers based on the PICO statement.
resultsThe search generated 3992 citations; 88 were included in the final database. SDH were significantly associated with a lower likelihood of fetal CHD diagnosis, higher CHD incidence and prevalence, increased infant mortality, adverse post-surgical outcomes (including hospital readmission and death), decreased healthcare access (including missed appointments, no shows, and loss to follow-up), impaired neurodevelopmental outcomes (including IQ and school performance) and quality of life, and adverse outcomes for adults with CHD (including endocarditis, hospitalization, and death).
conclusionsSDH are associated with a wide range of adverse outcomes for fetuses, children, and adults with CHD. SDH screening and referral to appropriate services has the potential to improve outcomes for CHD patients across the lifespan. IMPACT: Social determinants of health (SDH) are associated with a wide range of adverse outcomes for fetuses, children, and adults with congenital heart disease (CHD). This is the first systematic review (to our knowledge) on associations of SDH with congenital heart disease CHD outcomes. SDH screening and referral to appropriate services has the potential to improve outcomes for CHD patients across the lifespan.
Indexed as
Identifiers
33069160What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.