Evidence map›Paper›PMID 33068670›Full record

ArticleMagnetic resonance imaging2021

Intracranial vascular feature changes in time of flight MR angiography in patients undergoing carotid revascularization surgery.

Zhensen Chen, Li Chen, Manabu Shirakawa, Wenjin Liu, Dakota Ortega, Jinmei Chen, Niranjan Balu, Theodore Trouard, Thomas S Hatsukami, Wei Zhou and 1 more

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zhensen ChenDepartment of Radiology, University of Washington, Seattle, WA, USA. Electronic address: zhensenchen@gmail.com.
Li ChenDepartment of Electrical and Computer Engineering, University of Washington, Seattle, WA, USA.
Manabu ShirakawaDepartment of Radiology, University of Washington, Seattle, WA, USA.
Wenjin LiuDepartment of Radiology, University of Washington, Seattle, WA, USA.
Dakota OrtegaDepartment of Radiology, University of Washington, Seattle, WA, USA.
Jinmei ChenDepartment of Radiology, University of Washington, Seattle, WA, USA.
Niranjan BaluDepartment of Radiology, University of Washington, Seattle, WA, USA.
Theodore TrouardDepartment of Biomedical Engineering, The University of Arizona, Tuscon, AZ, USA.
Thomas S HatsukamiDepartment of Surgery, University of Washington, Seattle, WA, USA.
Wei ZhouDepartment of Surgery, The University of Arizona, Tuscon, AZ, USA.
Chun YuanDepartment of Radiology, University of Washington, Seattle, WA, USA.
University of Washington · USUniversity of Arizona · US

Funding

Carotid Intraplaque Hemorrhage: MRI of Therapeutic Response and Clinical SequelaeR01HL103609 · NHLBI · UNIVERSITY OF WASHINGTON · PI HATSUKAMI, THOMAS, YUAN, CHUN · 2011 to 2021
$7.1M
3D WALLI: MR intracranial vessel wall imaging for stroke preventionR01NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2016 to 2019
$3.1M
Long-term Cognitive Effects of Microembolization Associated with Carotid StentingR01NS070308 · NINDS · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI KRAEMER, FREDRIC B., ZHOU, WEI · 2011 to 2015
$1.9M
3D WALLI: MR intracranial vessel wall imaging for stroke preventionR56NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2015 to 2015
$609k
NHLBI NIH HHS R01 HL103609NINDS NIH HHS R01 NS070308NINDS NIH HHS R01 NS092207NINDS NIH HHS R56 NS092207
6 · The paper itself

Abstract

purposeTo characterize the intracranial vascular features extracted from time of flight (TOF) images and their changes from baseline to follow-up in patients undergoing carotid revascularization, using arterial spin labeling (ASL) cerebral blood flow (CBF) measurement as a reference.

methodsIn this retrospective study, brain TOF and ASL images of 99 subjects, acquired before, within 48 h, and/or 6 months after, carotid revascularization surgery were analyzed. TOF images were analyzed using a custom software (iCafe) to quantify intracranial vascular features, including total vessel length, total vessel volume, and number of branches. Mean whole-brain CBF was calculated from ASL images. ASL scans showing low ASL signal in the entire flow territory of an internal carotid artery (ICA), which may be caused by labeling failure, were excluded. Changes and correlations between time points were analyzed separately for TOF intracranial vascular features and ASL CBF.

resultsSimilar to ASL CBF, TOF vascular features (i.e. total vessel length, total vessel volume and number of branches) increased dramatically from baseline to post-surgery, then returned to a level slightly higher than the baseline in long-term follow-up (All P < 0.05). Correlation between time points was observed for all three TOF vascular features but not for ASL CBF.

conclusionIntracranial vascular features, including total vessel length, total vessel volume and number of branches, extracted from TOF images are useful in detecting brain blood flow changes induced by carotid revascularization surgery.

Indexed as

Cerebral RevascularizationImage Processing, Computer-AssistedMagnetic Resonance AngiographyAdultCarotid ArteriesCerebrovascular CirculationFemaleHumansMaleMiddle AgedRetrospective StudiesSoftwareCarotid revascularizationCerebral blood flowIntracranial vasculatureMagnetic resonance imagingTime of flight

Identifiers

PMID33068670
PMCPMC7739510
OpenAlexW3093419088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.