ArticlePlant cell reports2021
Vineyard environments influence Malbec grapevine phenotypic traits and DNA methylation patterns in a clone-dependent way.
Article in Plant cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- A dual genome-methylome map of clonal evolution in grapevine.Genome biology · 2026Article
- Trans-Generational Morphological Trait Plasticity in Parthenogenetic Offspring of TwoEcology and evolution · 2026Article
- Harnessing clonal diversity in grapevine: from genomic insights to modern breeding applications.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Natural genetic variation for fruit set rate within Malbec grapevine (Vitis vinifera L.) clones.BMC plant biology · 2025Article
- Diploid genome assembly of the Malbec grapevine cultivar enables haplotype-aware analysis of transcriptomic differences underlying clonal phenotypic variation.Horticulture research · 2024Article
- Emerging Roles of Epigenetics in Grapevine and Winegrowing.Plants (Basel, Switzerland) · 2024Review
- Genetic and Epigenetic Responses of Autochthonous Grapevine Cultivars from the 'Epirus' Region of Greece upon Consecutive Drought Stress.Plants (Basel, Switzerland) · 2023Article
- A Molecular Toolbox to Identify and Quantify Grape Varieties: On the Trace of "Glera".Foods (Basel, Switzerland) · 2023Article
- Characterization of the Rhizosphere Bacterial Microbiome and Coffee Bean Fermentation in the Castillo-Tambo and Bourbon Varieties in the Popayán-Colombia Plateau.BMC plant biology · 2023Article
- Metabolomic profiling of different clones of vitis vinifera L. cv. "Glera" and "Glera lunga" grapes by high-resolution mass spectrometry.Metabolomics : Official journal of the Metabolomic Society · 2023Article
- Exploring the crop epigenome: a comparison of DNA methylation profiling techniques.Frontiers in plant science · 2023Review
- Study of Inter- and Intra-varietal Genetic Variability in Grapevine Cultivars.Plants (Basel, Switzerland) · 2022Article
- Elevated transcription of transposable elements is accompanied by het-siRNA-driven de novo DNA methylation in grapevine embryogenic callus.BMC genomics · 2021Article
- Review
- Secondary Metabolism and Defense Responses Are Differently Regulated in Two Grapevine Cultivars during Ripening.International journal of molecular sciences · 2021Article
- Current status and prospects of plant genome editing in Australia.In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association · 2021Review
- Molecular Tools for Adapting Viticulture to Climate Change.Frontiers in plant science · 2021Review
- Epigenetic regulation and beyond in grapevine-pathogen interactions: a biotechnological perspective.Physiologia plantarumReview
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
key messageBy studying three cv. Malbec clones cultivated in two vineyards with contrasting environmental conditions, we demonstrated that DNA methylation has an important role in the phenotypic plasticity and that epigenetic modulation is clone-dependent. Clonal selection and vegetative propagation determine low genetic variability in grapevine cultivars, although it is common to observe diverse phenotypes. Environmental signals may induce epigenetic changes altering gene expression and phenotype. The range of phenotypes that a genotype expresses in different environments is known as phenotypic plasticity. DNA methylation is the most studied epigenetic mechanism, but only few works evaluated this novel source of variability in grapevines. In the present study, we analyzed the effects on phenotypic traits and epigenome of three Vitis vinifera cv. Malbec clones cultivated in two contrasting vineyards of Mendoza, Argentina. Anonymous genome regions were analyzed using methylation-sensitive amplified polymorphism (MSAP) markers. Clone-dependent phenotypic and epigenetic variability between vineyards were found. The clone that presented the clearer MSAP differentiation between vineyards was selected and analyzed through reduced representation bisulfite sequencing. Twenty-nine differentially methylated regions between vineyards were identified and associated to genes and/or promoters. We discuss about a group of genes related to hormones homeostasis and sensing that could provide a hint of the epigenetic role in the determination of the different phenotypes observed between vineyards and conclude that DNA methylation has an important role in the phenotypic plasticity and that epigenetic modulation is clone-dependent.
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