Evidence map›Paper›PMID 33068154›Full record

ArticleChromosoma2020

Genetic background impacts the timing of synaptonemal complex breakdown in Drosophila melanogaster.

Emily R Wesley, R Scott Hawley, Katherine Kretovich Billmyre

Abstract read
In one paragraph

Article in Chromosoma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The deubiquitinase Usp7 inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily R WesleyStowers Institute for Medical Research, Kansas City, MO, 64110, USA.
R Scott HawleyStowers Institute for Medical Research, Kansas City, MO, 64110, USA. rsh@stowers.org.ORCID 0000-0002-6478-0494
Katherine Kretovich BillmyreStowers Institute for Medical Research, Kansas City, MO, 64110, USA.

Funding

Uncovering mechanisms controlling chromosome-specific behaviors during meiosisK99GM138759 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI BILLMYRE, KATHERINE ELISABETH · 2020 to 2021
$200k
NIGMS NIH HHS K99 GM138759
6 · The paper itself

Abstract

Experiments performed in different genetic backgrounds occasionally exhibit failure in experimental reproducibility. This is a serious issue in Drosophila where there are no standard control stocks. Here, we illustrate the importance of controlling genetic background by showing that the timing of a major meiotic event, the breakdown of the synaptonemal complex (SC), varies in different genetic backgrounds. We assessed SC breakdown in three different control stocks and found that in one control stock, y w; sv

Indexed as

Genetic BackgroundAllelesAnimalsCell DifferentiationChromosome SegregationDrosophila melanogasterEmbryonic DevelopmentGenetic Association StudiesGenotypeHeterozygoteMolecular ImagingMutationOocytesSynaptonemal ComplexGenetic backgroundMeiosisSynaptonemal complex

Identifiers

PMID33068154
PMCPMC7666587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.