Evidence map›Paper›PMID 33068118›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2021

Identification through fine mapping and verification using CRISPR/Cas9-targeted mutagenesis for a minor QTL controlling grain weight in rice.

Aye Nyein Chan, Lin-Lin Wang, Yu-Jun Zhu, Ye-Yang Fan, Jie-Yun Zhuang, Zhen-Hua Zhang

Open access · hybridAbstract read
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Plants (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Fine Mapping ofInternational journal of molecular sciences · 2022
    Article
  15. Frontiers in plant science · 2022
    Article
  16. Control of Thousand-Grain Weight byInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aye Nyein ChanState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China.
Lin-Lin WangState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China.
Yu-Jun ZhuState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China.
Ye-Yang FanState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China.
Jie-Yun ZhuangState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China. zhuangjieyun@caas.cn.ORCID http://orcid.org/0000-0002-1439-5061
Zhen-Hua ZhangState Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement, China National Rice Research Institute, Hangzhou, 310006, China. zhangzhenhua@caas.cn.ORCID http://orcid.org/0000-0003-0711-7466
China National Rice Research Institute · CNYezin Agricultural University · MM

Funding

National Natural Science Foundation of China 31701072Organization for Women in Science for the Developing World and Swedish International Development Cooperation Agency 3240303476Zhejiang Provincial Natural Science Foundation of China LQ17C130004Zhejiang Provincial Natural Science Foundation of China LQ18C130002
6 · The paper itself

Abstract

key messageA minor QTL for grain weight in rice, qTGW1.2b, was fine-mapped. Its casual gene OsVQ4 was confirmed through CRISPR/Cas9-targeted mutagenesis, exhibiting an effect that was larger than the original QTL effect. The CRISPR/Cas system exhibits a great potential for rice improvement, but the application was severely hindered due to insufficient target genes, especial the lack of validated genes underlying quantitative trait loci having small effects. In this study, a minor QTL for grain weight, qTGW1.2b, was fine-mapped into a 44.0 kb region using seven sets of near isogenic lines (NILs) developed from the indica rice cross (Zhenshan 97)

Indexed as

Quantitative Trait LociChromosome MappingCRISPR-Cas SystemsGene EditingGene Knockout TechniquesGenes, PlantMutagenesisOryzaSeeds

Identifiers

PMID33068118
PMCPMC7813696
OpenAlexW3092989312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.