Evidence map›Paper›PMID 33068043›Full record

ArticleHuman brain mapping2021

Mindfulness-based cognitive therapy on bereavement grief: Alterations of resting-state network connectivity associate with changes of anxiety and mindfulness.

Feng-Ying Huang, Ai-Ling Hsu, Yi-Ping Chao, Chloe Mu-Hsuan Shang, Jaw-Shiun Tsai, Changwei W Wu

Abstract read
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Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
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  3. Prolonged grief disorder in later life: advancing our understanding of biopsychosocial mechanisms to guide future personalized interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Feng-Ying HuangDepartment of Education, National Taipei University of Education, Taipei, Taiwan.
Ai-Ling HsuDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Yi-Ping ChaoGraduate Institute of Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan.
Chloe Mu-Hsuan ShangDepartment of Psychology, University of Michigan, Ann Arbor, Michigan, USA.
Jaw-Shiun TsaiDepartment of Family Medicine, College of Medicine and Hospital, National Taiwan University, Taipei, Taiwan.
Changwei W WuGraduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0001-8968-9366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bereavement, the experience of losing a loved one, is one of the most catastrophic but inevitable events in life. It causes grief and intense depression-like sadness. Recent studies have revealed the effectiveness and proficiency of mindfulness-based cognitive therapy (MBCT) in emotional regulation among bereavement populations. MBCT improves the well-being of the bereaved by enhancing cognitive performances. Regarding the neural correlates of bereavement grief, previous studies focused on the alleviation of emotion-cognition interferences at specific brain regions. Here, we hypothesized that the bereavement grief fundamentally triggers global alterations in the resting-state brain networks and part of the internetwork connectivity could be reformed after MBCT intervention. We recruited 19 bereaved individuals who participated the 8-week MBCT program. We evaluated (a) the large-scale changes in brain connectivity affected by the MBCT program; as well as (b) the association between connectivity changes and self-rated questionnaire. First, after MBCT, the bereaved individuals showed the reduction of the internetwork connectivity in the salience, default-mode and fronto-parietal networks in the resting state but not under emotional arousal, implying the alleviated attention to spontaneous mind wandering after MBCT. Second, the alterations of functional connectivity between subcortical (e.g., caudate) and cortical networks (e.g., cingulo-opercular/sensorimotor) were associated with the changes of the mindfulness scale, the anxiety and the emotion regulation ability. In summary, MBCT could enhance spontaneous emotion regulation among the bereaved individuals through the internetwork reorganizations in the resting state.

Indexed as

BereavementAdultAgedAnxietyBrainCognitive Behavioral TherapyFemaleGriefHumansMagnetic Resonance ImagingMaleMiddle AgedMindfulnessNerve NetProspective StudiesRestbereavementemotion regulationfunctional connectivityfunctional magnetic resonance imaginggriefmindfulness-based cognitive therapy

Identifiers

PMID33068043
PMCPMC7775995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.