Evidence map›Paper›PMID 33068021›Full record

Trial reportAmerican journal of hematology2021

Involved free light chains <10 mg/L with treatment predict better outcomes in systemic light-chain amyloidosis.

Amandeep Godara, Denis Toskic, Jack Albanese, Benjamin Rosenthal, Nauman S Siddiqui, Adin Kugelmass, Ping Zhou, Teresa Fogaren, Cindy Varga, Heather J Landau and 1 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in American journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cardiac Amyloidosis.Heart failure clinics · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amandeep GodaraJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.ORCID 0000-0003-1943-4442
Denis ToskicJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.ORCID 0000-0002-3340-762X
Jack AlbaneseJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Benjamin RosenthalJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Nauman S SiddiquiDivision of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Adin KugelmassJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Ping ZhouJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Teresa FogarenJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Cindy VargaJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Heather J LandauDivision of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Raymond L ComenzoJohn Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Screening to Improve Survival in AL AmyloidosisR21AG070502 · NIA · TUFTS MEDICAL CENTER · PI COMENZO, RAYMOND LUKE, LENTZSCH, SUZANNE · 2020 to 2021
$515k
NCI NIH HHS P30 CA008748NIA NIH HHS R21 AG070502
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunoglobulin Light-chain AmyloidosisDisease-Free SurvivalFemaleFollow-Up StudiesHumansImmunoglobulin Light ChainsMaleMiddle AgedSurvival RateImmunoglobulin Light Chains

Identifiers

PMID33068021
PMCPMC8436337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.