Evidence map›Paper›PMID 33067997›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2021

Functional Connectivity Network Disruption Underlies Domain-Specific Impairments in Attention for Children Born Very Preterm.

M D Wheelock, R E Lean, S Bora, T R Melzer, A T Eggebrecht, C D Smyser, L J Woodward

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Prenatal Adversity and Neonatal Brain Connectivity Relate to Emerging Executive Function at Age 2 Years.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in neuroscience · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M D WheelockDepartment of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
R E LeanDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63108, USA.
S BoraMothers, Babies, and Women's Health Program, Mater Research Institute, University of Queensland, South Brisbane, Australia.
T R MelzerDepartment of Medicine, University of Otago, New Zealand Brain Research Institute, Christchurch 8011, New Zealand.
A T EggebrechtDepartment of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
C D SmyserDepartment of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
L J WoodwardSchool of Health Sciences and Child Wellbeing Research Institute, University of Canterbury, Christchurch 8041, New Zealand.

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
proj 3 - NINDS INSTIUTIONAL CENTER CORE GRANTS TO SUPPORT NEUROSCIENCE RESEARP30NS048056 · NINDS · WASHINGTON UNIVERSITY · PI MINTUN, MARK A. · 2004 to 2014
$7.4M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Developmental Neuroscience and Child PsychopathologyT32MH100019 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, JOAN L. LUBY · 2013 to 2026
$4.8M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
IMAGING BRAIN FUNCTION IN CHILDREN WITH AUTISM SPECTRUM DISORDERS WITH DIFFUSE OPTICAL TOMOGRAPHYK01MH103594 · NIMH · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2015 to 2019
$708k
Network level analysis of progressive brain degeneration in autosomal dominant Alzheimer diseaseK99EB029343 · NIBIB · WASHINGTON UNIVERSITY · PI WHEELOCK, MURIAH D · 2020 to 2021
$484k
NIBIB NIH HHS K99 EB029343NICHD NIH HHS P50 HD103525NICHD NIH HHS U54 HD087011NIMH NIH HHS K01 MH103594NIMH NIH HHS R01 MH113570NIMH NIH HHS T32 MH100019NINDS NIH HHS K02 NS089852NINDS NIH HHS P30 NS048056
6 · The paper itself

Abstract

Attention problems are common in school-age children born very preterm (VPT; < 32 weeks gestational age), but the contribution of aberrant functional brain connectivity to these problems is not known. As part of a prospective longitudinal study, brain functional connectivity (fc) was assessed alongside behavioral measures of selective, sustained, and executive attention in 58 VPT and 65 full-term (FT) born children at corrected-age 12 years. VPT children had poorer sustained, shifting, and divided attention than FT children. Within the VPT group, poorer attention scores were associated with between-network connectivity in ventral attention, visual, and subcortical networks, whereas between-network connectivity in the frontoparietal, cingulo-opercular, dorsal attention, salience and motor networks was associated with attention functioning in FT children. Network-level differences were also evident between VPT and FT children in specific attention domains. Findings contribute to our understanding of fc networks that potentially underlie typical attention development and suggest an alternative network architecture may help support attention in VPT children.

Indexed as

Infant, Extremely PrematureAttentionBrainChildConnectomeFemaleHumansInfant, NewbornLongitudinal StudiesMagnetic Resonance ImagingMaleNerve NetProspective Studiesattentionfunctional connectivitynetworksoutcomepreterm

Identifiers

PMID33067997
PMCPMC8179512

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.