ArticleJournal of clinical laboratory analysis2021
Thromboelastography (TEG) in normal pregnancy and its diagnostic efficacy in patients with gestational hypertension, gestational diabetes mellitus, or preeclampsia.
Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 22 citations in OpenAlex.
- The value of coagulation index in thromboelastography for predicting early pregnancy loss in in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles.Scientific reports · 2026Article
- Rotational Thromboelastometry (ROTEM) Hemostasis Profile in Pregnant Women with Preeclampsia and Their Offspring: An Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- Case-control study of clotting differences using ROTEM testing in pregnant patients with early vaginal bleeding.European journal of obstetrics, gynecology, and reproductive biology · 2025Article
- Maternal and fetal outcomes in 151 cases of thrombocytopenia in pregnancy.Frontiers in cell and developmental biology · 2025Article
- Application of thromboelastogram and coagulation function in evaluating coagulation status of pregnant women across different trimesters.Frontiers in medicine · 2025Article
- Hemostasis in Pre-Eclamptic Women and Their Offspring: Current Knowledge and Hemostasis Assessment with Viscoelastic Tests.Diagnostics (Basel, Switzerland) · 2024Review
- Application of thromboelastography in diagnosing normal pregnancies and pregnancies with complications.Journal of clinical laboratory analysis · 2022Observational
- Detection of Hemostasis Abnormalities in Type 2 Diabetes Mellitus Using Thromboelastography.Journal of the ASEAN Federation of Endocrine Societies · 2022Article
- Thromboelastography (TEG) in normal pregnancy and its diagnostic efficacy in patients with gestational hypertension, gestational diabetes mellitus, or preeclampsia.Journal of clinical laboratory analysis · 2021Article
- The Use of the Maximum Amplitude Parameter in Thromboelastography for Obstetric Anesthesiology: A Retrospective Study Conducted at a University Medical Center.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Clinical Application of Thromboelastography in Patients With Severe Fever With Thrombocytopenia Syndrome.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Diagnostic Value of Thromboelastography (TEG) for the Diagnosis of Death in Infected Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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15 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThromboelastography (TEG) provides global assessment of hemostatic function and has been recommended to monitor potential coagulopathies during pregnancy in which hypercoagulable state is favored. In present study, we established the reference intervals (RIs) of the TEG parameters (R, K, MA, and α-angle) with Chinese pregnant women of third trimester. In addition, we examined the diagnostic efficacies of the TEG parameters in the patients diagnosed of gestational hypertension (GH), gestational diabetes mellitus (GDM), or preeclampsia (PE).
methodsWith specified including and excluding criteria, non-pregnant controls, healthy pregnant women, and pregnant women with GH, GDM, or PE had their venous blood drawn at Beijing Obstetrics and Gynecology Hospital, followed by TEG tests performed in the clinical laboratory.
resultsThe RIs determined with the healthy pregnant women (in third trimester) for R, K, MA, and α-angle were 4.0-7.7, 1.2-3.2, 51.9-70.1, and 41.4-74.4, respectively. When compared with the healthy pregnancy group, the K value was significantly decreased in GH patients but increased in PE patients; MA was significantly lower in the PE group. In the receiver operating characteristic curve (ROC) analyses, K value was able to efficiently distinguish normal pregnancy from the GH patients, with an AUC of 0.86 which is far better than those of R (AUC = 0.57) and MA (AUC = 0.56). For the PE patients, the AUC of MA (0.69) was significantly greater than that of R (0.50).
conclusionsThromboelastography may provide more accurate experimental basis for monitoring coagulation functions especially in pregnant women with complications of GH and PE.
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