Evidence map›Paper›PMID 33067802›Full record

ArticleAlcoholism, clinical and experimental research2020

Health System-Based Unhealthy Alcohol Use Screening and Treatment Comparing Demographically Matched Participants With and Without HIV.

Michael J Silverberg, Tory Levine-Hall, Nicole Hood, Alexandra N Anderson, Stacey E Alexeeff, Jennifer O Lam, Sally B Slome, Jason A Flamm, Charles Bradley Hare, Thekla Ross and 8 more

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cardiovascular Disease Risk Factor Control in People With and Without HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  8. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Michael J SilverbergFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.ORCID 0000-0001-9322-1395
Tory Levine-HallFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Nicole HoodFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Alexandra N AndersonFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Stacey E AlexeeffFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Jennifer O LamFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Sally B SlomeOakland Medical Center, (SBS), KPNC, Oakland, California.
Jason A FlammSacramento Medical Center, (JAF), KPNC, Sacramento, California.
Charles Bradley HareSan Francisco Medical Center, (CBH), KPNC, San Francisco, California.
Thekla RossFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Amy C JusticeYale School of Medicine, (AJ), Yale University, West Haven, Connecticut.
Jonathan A C SterneDepartment of Population Health Sciences, (JACS), Bristol Medical School, University of Bristol, Bristol, UK.
Andrew E WilliamsTufts Medical Center, (AEW), Boston, Massachusetts.ORCID 0000-0002-0692-412X
Kendall J BryantNational Institute on Alcohol Abuse and Alcoholism, (KJB), National Institutes of Health, Bethesda, Maryland.
Constance M WeisnerFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Michael A HorbergMid-Atlantic Permanente Research Institute, (MAH), Kaiser Permanente Mid-Atlantic States, Rockville, Maryland.
Stacy A SterlingFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.
Derek D SatreFrom the, Division of Research, (MJS, TL-H, NH, ANA, SEA, JOL, TR, CMW, SAS, DDS), Kaiser Permanente Northern California (KPNC), Oakland, California.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Tufts Clinical and Translational Science Institute (Pilot Supplement)UL1TR002544 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2018 to 2022
$50.2M
2/3 COMpAAAS Tripartite: ART-CC, KP, and VAU01AA026230 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI SATRE, DEREK D, SILVERBERG, MICHAEL J · 2017 to 2021
$3.0M
1/3 Collaborative Research in HIV/AIDS, Alcohol, and Related Comorbidities (COMpAAAS) Tripartite: ART-CC, KP, and VAU01AA026209 · NIAAA · UNIVERSITY OF BRISTOL · PI STERNE, JONATHAN · 2017 to 2021
$2.2M
Mentoring alcohol use intervention research in HIV health care settingsK24AA025703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre · 2018 to 2026
$1.8M
Population-based Screening and Brief Intervention in Primary Care: Health and Drinking Outcomes, Cost and UtilizationR01AA025902 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI STERLING, STACY ANN · 2017 to 2020
$1.6M
Medical Research Council G0100221Medical Research Council G0700820Medical Research Council MR/J002380/1NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002544NIAAA NIH HHS K24 AA025703NIAAA NIH HHS R01 AA025902NIAAA NIH HHS U01 AA026209NIAAA NIH HHS U01 AA026230
6 · The paper itself

Abstract

backgroundUnhealthy alcohol use among persons living with HIV (PLWH) is linked to significant morbidity, and use of alcohol services may differ by HIV status. Our objective was to compare unhealthy alcohol use screening and treatment by HIV status in primary care.

methodsCohort study of adult (≥18 years) PLWH and HIV-uninfected participants frequency matched 20:1 to PLWH by age, sex, and race/ethnicity who were enrolled in a large integrated healthcare system in the United States, with information ascertained from an electronic health record. Outcomes included unhealthy alcohol screening, prevalence, provider-delivered brief interventions, and addiction specialty care visits. Other predictors included age, sex, race/ethnicity, neighborhood deprivation index, depression, smoking, substance use disorders, Charlson comorbidity index, prior outpatient visits, insurance type, and medical facility. Cox proportional hazards models were used to compute hazard ratios (HR) for the outcomes of time to unhealthy alcohol use screening and time to first addiction specialty visit. Poisson regression with robust standard errors was used to compute prevalence ratios (PR) for other outcomes.

results11,235 PLWH and 227,320 HIV-uninfected participants were included. By 4.5 years after baseline, most participants were screened for unhealthy alcohol use (85% of PLWH and 93% of HIV-uninfected), but with a lower rate among PLWH (adjusted HR 0.84, 95% CI 0.82 to 0.85). PLWH were less likely, compared with HIV-uninfected participants, to report unhealthy drinking among those screened (adjusted PR 0.74, 95% CI 0.69 to 0.79), and among those who screened positive, less likely to receive brief interventions (adjusted PR 0.82, 95% CI 0.75 to 0.90), but more likely (adjusted HR 1.7, 95% CI 1.2 to 2.4) to have an addiction specialty visit within 1 year.

conclusionsUnhealthy alcohol use was lower in PLWH, but the treatment approach by HIV status differed. PLWH reporting unhealthy alcohol use received less brief interventions and more addiction specialty care than HIV-uninfected participants.

Indexed as

AlcoholismCase-Control StudiesDelivery of Health Care, IntegratedFemaleHIV InfectionsHumansMaleMass ScreeningMiddle AgedPoisson DistributionPrimary Health CareProportional Hazards ModelsAlcohol UseEpidemiologyHIVPrimary CareSubstance Abuse

Identifiers

PMID33067802
PMCPMC7725961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.