Evidence map›Paper›PMID 33067743›Full record

SynthesisAnnals of surgical oncology2021

A Systematic Review Comparing Emergency Resection and Staged Treatment for Curable Obstructing Right-Sided Colon Cancer.

Jeske R E Boeding, Winesh Ramphal, Arjen M Rijken, Rogier M P H Crolla, Cornelis Verhoef, Paul D Gobardhan, Jennifer M J Schreinemakers

Open access · hybridAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Annals of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Bridge-to-surgery in acute right-sided obstructing colon cancer: A survey of surgeons' perspectives on treatment strategies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article
  4. Article
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  8. The effect of combined head and tail approach during laparoscopic D3 lymph node dissection on pain severity and complications in patients with right colon cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  9. Review
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  12. Review
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  16. Review
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  19. Article
  20. Colonic Stenting in the Emergency Setting.Medicina (Kaunas, Lithuania) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jeske R E BoedingDepartment of Surgery, Amphia Hospital, Breda, The Netherlands. jeskeboeding@gmail.com.ORCID http://orcid.org/0000-0002-7910-9302
Winesh RamphalDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
Arjen M RijkenDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
Rogier M P H CrollaDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
Cornelis VerhoefDepartment of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Paul D GobardhanDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
Jennifer M J SchreinemakersDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
Amphia Ziekenhuis · NLErasmus MC Cancer Institute · NL

Funding

Wetenschapsfonds Amphia 2018-5
6 · The paper itself

Abstract

backgroundTreatment for obstructing colon cancer (OCC) is controversial because the outcome of acute resection is less favorable than for patients without obstruction. Few studies have investigated curable right-sided OCC, and patients with OCC usually undergo acute resection. This study aimed to better understand the outcome and best management of potentially curable right-sided OCC.

methodsA systematic review of studies was performed with a focus on differences in mortality and morbidity between emergency resection and staged treatment for patients with potentially curable right-sided OCC. In March 2019, the study searched Embase, Medline, Web of Science, Cochrane, and Google scholar databases according to PRISMA guidelines using search terms related to "colon tumour," "stenosis or obstruction and surgery," and "decompression or stents." All English-language studies reporting emergency or staged treatment for potentially curable right-sided OCC were included in the review. Emergency resection and staged resection were compared for mortality, morbidity, complications, and survival.

resultsNine studies were found to be eligible and comprised 600 patients treated with curative intent for their right-sided OCC by emergency resection or staged resection. The mean overall complication rate was 42% (range 19-54%) after emergency resection, and 30% (range 7-44%) after staged treatment. The average mortality rate was 7.2% (range 0-14.5%) after emergency resection and 1.2% (range 0-6.3%) after staged treatment. The 5-year disease-free and overall survival rates were comparable for the two treatments.

conclusionsThe patients who received staged treatment for right-sided OCC had lower mortality rates, fewer complications, and fewer anastomotic leaks and stoma creations than the patients who had emergency resection.

Indexed as

Colonic NeoplasmsIntestinal ObstructionEmergency TreatmentHumansRetrospective StudiesTreatment Outcome

Identifiers

PMID33067743
OpenAlexW3093459729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.