Observational studyWorld journal of urology2021
Quality of life and functional outcomes after radical cystectomy with ileal orthotopic neobladder replacement for bladder cancer: a multicentre observational study.
Observational study in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Comparison of morbidity and mortality after radical cystectomy between individuals older and younger than 80 years: a systematic review and meta-analysis.International urology and nephrology · 2024Pooled it
- The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Pooled it
- Preclinical development of engineered biomaterial-based artificial bladder demonstrating core functions in a large-animal orthotopic model.Materials today. Bio · 2026Article
- Article
- Anterograde release of the neurovascular bundle during nerve-sparing robot-assisted radical cystectomy: initial experience and functional outcomes in males from a case-series.Translational andrology and urology · 2026Article
- Efficacy evaluation of urethral dragging-and-adhesion anastomosis in ileal orthotopic neobladder reconstruction following laparoscopic radical cystectomy: a dual-center retrospective study.Frontiers in surgery · 2026Article
- Article
- Comparative outcomes of internal, external, and no stent in ureteroileal anastomosis for ileal orthotopic neobladder reconstruction.Translational andrology and urology · 2025Article
- Elderly and bladder cancer: The role of radical cystectomy and orthotopic urinary diversion.Urologia · 2024Review
- A systematic review of the patient reported outcomes that affect patients with muscle invasive bladder cancer after radical cystectomy and urinary diversion.BJUI compass · 2024Review
- Role performance and factors affecting quality of life in bladder cancer survivors with ileal orthotopic neobladder.Asia-Pacific journal of oncology nursing · 2024Article
- Laparoscopic Radical Cystectomy with Ileal Orthotopic Neobladder for Bladder Cancer: Current Indications and Outcomes.Urologia internationalis · 2024Review
- Development and evaluation of a rehabilitation training compliance scale for patients with urinary incontinence.BMC nursing · 2023Article
- Health-related quality of life after curative treatment for muscle-invasive bladder cancer.Nature reviews. Urology · 2023Review
- Neobladder "Function": Tips and Tricks for Surgery and Postoperative Management.Life (Basel, Switzerland) · 2022Review
- Pelvic reconstruction and lateral prostate capsule sparing techniques improve early continence of robot-assisted radical cystectomy with orthotopic ileal neobladder.International urology and nephrology · 2022Article
- Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery.World journal of urology · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIleal orthotopic neobladder (IONB) reconstruction is the preferred urinary diversion among selected patients who have undergone radical cystectomy (RC) for bladder cancer (BCa). There is insufficient data regarding patients' quality of life (QoL), sexual and urinary outcomes. Our objectives were to assess QoL in a multicentre cohort study, and to identify related clinical, oncological and functional factors.
methodsPatients who underwent RC with IONB reconstruction for BCa from 2010 to 2017 at one of the three French hospitals completed the following self-reported questionnaires: European Organization for Research and Treatment of Cancer (EORTC) generic (QLQ-C30) and bladder cancer specific instruments (QLQ-BLM30). To assess urinary symptoms, patients completed the Urinary Symptom Profile questionnaire (USP) and a three-day voiding diary. Univariate and multivariate analyses were computed to identify clinical, pathological, and functional predictors of global QoL score.
resultsSeventy-three patients completed questionnaires. The median age was 64 years and 86.3% were men. The median interval between surgery and responses to questionnaires was 36 months (range 12-96). Fifty-five percent of patients presented a high global QoL (EORTC-QLQC30, median score 75). A pre-RC American Society of Anesthesiologists score > 2, active neoplasia, sexual inactivity, and stress urinary incontinence were associated with a worse QoL. After a multivariate analysis, sexual inactivity was the only independent factor related to an altered QoL.
conclusionPatients with IONB reconstruction after RC have a high global QoL. Sexual activity could independently impact the global QoL, and it should be assessed pre- and post-operatively by urologists.
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