Evidence map›Paper›PMID 33067705›Full record

ArticleLasers in medical science2021

Reflectance confocal microscopy evaluation of pigmented lesions on tattooed skin.

Catherine Reilly, Nadiya Chuchvara, Jennifer Cucalon, Radhika Srivastava, Babar K Rao

Abstract read
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In one paragraph

Article in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Characteristics of exogenous pigment diseases under reflectance confocal microscopy.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catherine ReillyRao Dermatology, 95 First Avenue, Atlantic Highlands, NJ, 07716, USA. clarkcat@sas.upenn.edu.ORCID http://orcid.org/0000-0001-7921-4762
Nadiya ChuchvaraRao Dermatology, 95 First Avenue, Atlantic Highlands, NJ, 07716, USA.
Jennifer CucalonRao Dermatology, 95 First Avenue, Atlantic Highlands, NJ, 07716, USA.
Radhika SrivastavaRao Dermatology, 95 First Avenue, Atlantic Highlands, NJ, 07716, USA.
Babar K RaoRao Dermatology, 95 First Avenue, Atlantic Highlands, NJ, 07716, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evaluation of pigmented lesions on tattooed skin poses a diagnostic challenge for dermatologists, as a nevus may be partially or completely obscured by tattoo pigment. Because of incidences of melanoma arising from tattooed skin, the current gold standard is to biopsy these lesions. Reflectance confocal microscopy (RCM) is a noninvasive imaging modality used in the diagnosis and management of skin diseases that may allow for diagnosis, while preserving the tattoo design. Retrospective chart review was conducted to identify pigmented lesions on or near tattooed skin that were evaluated with RCM. Confocal characteristics and diagnoses were recorded and analyzed. Nineteen lesions from 15 patients were retrospectively reviewed. Tattoo pigment did not hinder evaluation and diagnosis of pigmented lesions on RCM. About 94.7% of lesions were diagnosed as benign melanocytic nevi by an expert confocal reader. One lesion was confocally diagnosed as melanocytic nevus with atypia but was found to be an inflamed melanocytic nevus on histology. Tattoo pigment particles were differentiated from other hyper-refractile entities by an expert confocal reader based on size, morphology, and clinical correlation. RCM may provide a solution to the diagnostic challenge of pigmented lesions on or near tattooed skin.

Indexed as

Microscopy, ConfocalTattooingBiopsyDiagnosis, DifferentialHumansMaleNevus, PigmentedRetrospective StudiesSkinDermatologyDermoscopyIn vivoNon-invasivePediatricPigmented lesionsRCMReflectance confocal microscopyTattoo

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.