Evidence map›Paper›PMID 33067683›Full record

ReviewApplied microbiology and biotechnology2020

Recent advances in biocatalytic derivatization of L-tyrosine.

Xu Tan, Wei Song, Xiulai Chen, Liming Liu, Jing Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xu TanSchool of Pharmaceutical Science, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Wei SongSchool of Pharmaceutical Science, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Xiulai ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China.
Liming LiuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China.
Jing WuSchool of Pharmaceutical Science, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China. wujing@jiangnan.edu.cn.
State Key Laboratory of Food Science and Technology · CNJiangnan University · CN

Funding

Key Technologies R & D Program of Jiangsu Province BE2018623national first-class discipline program of Light Industry Technology and Engineering LITE2018-20National Natural Science Foundation of China 21878126
6 · The paper itself

Abstract

L-Tyrosine is an aromatic, polar, non-essential amino acid that contains a highly reactive α-amino, α-carboxyl, and phenolic hydroxyl group. Derivatization of these functional groups can produce chemicals, such as L-3,4-dihydroxyphenylalanine, tyramine, 4-hydroxyphenylpyruvic acid, and benzylisoquinoline alkaloids, which are widely employed in the pharmaceutical, food, and cosmetics industries. In this review, we summarize typical L-tyrosine derivatizations catalyzed by enzymatic biocatalysts, as well as the strategies and challenges associated with their production processes. Finally, we discuss future perspectives pertaining to the enzymatic production of L-tyrosine derivatives.Key points• Summary of recent advances in enzyme-catalyzed L-tyrosine derivatization.• Highlights of relevant strategies involved in L-tyrosine derivatives biosynthesis.• Future perspectives on industrial applications of L-tyrosine derivatization.

Indexed as

Amino AcidsTyrosineBiocatalysisAmino AcidsTyrosineDerivatizationEnzyme catalysisGroup modificationL-Tyrosine

Identifiers

PMID33067683
OpenAlexW3092683163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.