Evidence map›Paper›PMID 33067675›Full record

ArticleUpdates in surgery2021

Changes in gut microbial flora after Roux-en-Y gastric bypass and sleeve gastrectomy and their effects on post-operative weight loss.

Reza Karami, Mohammad Kermansaravi, Mohaddese Pishgahroudsari, Malihe Talebi, Nima Mohammadzadeh, Abdolreza Pazouki

Abstract read
PubMed Publisher
In one paragraph

Article in Updates in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Reza KaramiMinimally Invasive Surgery Research Center, Iran University of Medical Sciences, Rasool-E-Akram Hospital, Tehran, Iran.
Mohammad KermansaraviMinimally Invasive Surgery Research Center, Iran University of Medical Sciences, Rasool-E-Akram Hospital, Tehran, Iran. mkermansaravi@yahoo.com.ORCID http://orcid.org/0000-0001-8978-9359
Mohaddese PishgahroudsariBS, Statistics Analyzer, Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran.
Malihe TalebiDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nima MohammadzadehDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Abdolreza PazoukiMinimally Invasive Surgery Research Center, Iran University of Medical Sciences, Rasool-E-Akram Hospital, Tehran, Iran.
Iran University of Medical Sciences · IR

Funding

Iran University of Medical Sciences 95-02-140-27464
6 · The paper itself

Abstract

Bariatric surgery affects gut microbial flora due to the anatomical and physiological changes it causes in the gastrointestinal tract. Understanding the interaction between the gut flora, the type of bariatric surgery and weight loss may help improve bariatric surgery outcomes. This study was designed to compare the effects of Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) on two main phyla of the gut microbiota in humans and evaluate their potential effect on weight changes. Thirty morbidly obese patients were divided into two groups and underwent laparoscopic SG or laparoscopic RYGB. The patients' weight changes and fecal samples were evaluated at baseline and 6 months after the surgery. A microbial flora count was carried out of the phyla Bacteroidetes and Firmicutes and Bacteroides Fragilis. Changes in the abundance of the flora and their correlation with weight loss were analyzed. After 6 months, the patients with a history of RYGB showed a significant decrease in stool Bacteroidetes while the reduction in the SG group was insignificant. Firmicutes abundance was almost unchanged following SG and RYGB. There was no significant change in Bacteroides Fragilis abundance in either of the two groups, but a positive correlation was observed between Bacteroides Fragilis and weight loss after SG and RYGB. Bariatric surgery can affect gut microbiota. It can be concluded that these changes are dependent on many factors and may play a role in weight loss.

Indexed as

Gastric BypassGastrointestinal MicrobiomeObesity, MorbidGastrectomyHumansWeight LossMicrobial floraRoux en Y gastric bypassSleeve gastrectomyWeight

Identifiers

PMID33067675
OpenAlexW3093240800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.