Evidence map›Paper›PMID 33067663›Full record

ArticleLung2020

Influence of Cystic Fibrosis-Related Diabetes on Mental Health in Adults: A Single-Center Study.

Michelle Hjelm, Dmitry Tumin, Christopher J Nemastil, Ann E Salvator, Don Hayes

Erratum issuedAbstract read
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In one paragraph

Article in Lung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Evolving nutrition therapy in cystic fibrosis: Adapting to the CFTR modulator era.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Review
  3. Cystic Fibrosis-Related Diabetes in Poland.International journal of environmental research and public health · 2022
    Article
  4. Cystic fibrosis-related diabetes: The patient perspective.Journal of clinical & translational endocrinology · 2021
    Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Michelle HjelmDivision of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA. michelle.hjelm@cchmc.org.ORCID http://orcid.org/0000-0003-4474-8021
Dmitry TuminDepartment of Pediatrics, Brody School of Medicine At East Carolina University, Greenville, NC, USA.
Christopher J NemastilDivision of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Ann E SalvatorBureau of Infectious Disease, Ohio Department of Health, Columbus, OH, USA.
Don HayesDivision of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.

Funding

Cystic Fibrosis Foundation HJELM16B0; HJELM18A0-D3
6 · The paper itself

Abstract

purposePeople with cystic fibrosis (CF) are predisposed to chronic conditions, such as CF-related diabetes (CFRD). Recent attention has been focused on the addition of screening for anxiety and depression in the CF population. Independently, CFRD and mental health conditions are associated with worse clinical outcomes; however, research assessing the impact of both conditions together is limited. We aimed to characterize the association between CFRD and selected diagnoses of anxiety or depressive disorders on clinical outcomes in adults with CF.

methodsA single-center, retrospective, cross-sectional study in adult patients with CF was performed. Group comparisons included selected diagnoses of depression, anxiety, and CFRD using two-sample t-tests or rank-sum tests for continuous variables, and Chi-square or Fisher's exact tests for categorical variables.

resultsA total of 209 adults were enrolled (mean age of 31.4 ± 11.4 years). Those with a selected diagnoses of depression had a significantly higher proportion of CFRD than those without depression (48% vs. 28%, respectively, p = 0.005), and CFRD was associated with increased odds of depression [OR (CI) = 2.33 (1.28, 4.26), p = 0.006]. We did not see a higher proportion of adults with CFRD and selected diagnoses of anxiety than those without anxiety (41% vs. 31% respectively, p = 0.12), nor an increased odds of anxiety in those with CFRD [OR (CI) = 1.58 (0.88, 2.84), p = 0.12].

conclusionWe show a significant association between CFRD and selected diagnoses of depression in a cohort of adult patients.

Indexed as

AdolescentAdultAgedAnxiety DisordersCross-Sectional StudiesCystic FibrosisDepressive DisorderDiabetes ComplicationsFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultAnxietyCystic fibrosisCystic fibrosis-related diabetesdepression

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.