Evidence map›Paper›PMID 33067406›Full record

ArticleNeurology2020

Exploring the relationship between effort perception and poststroke fatigue.

William De Doncker, Lucie Charles, Sasha Ondobaka, Annapoorna Kuppuswamy

Abstract read
In one paragraph

Article in Neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. The Neurobiology of Pathological Fatigue: New Models, New Questions.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2022
    Article
  13. Review
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William De DonckerFrom the Department of Clinical and Movement Neuroscience, (W.D.D., S.O., A.K.) Institute of Neurology, and Institute of Cognitive Neuroscience (L.C., S.O.), UCL, London, UK.
Lucie CharlesFrom the Department of Clinical and Movement Neuroscience, (W.D.D., S.O., A.K.) Institute of Neurology, and Institute of Cognitive Neuroscience (L.C., S.O.), UCL, London, UK.
Sasha OndobakaFrom the Department of Clinical and Movement Neuroscience, (W.D.D., S.O., A.K.) Institute of Neurology, and Institute of Cognitive Neuroscience (L.C., S.O.), UCL, London, UK.
Annapoorna KuppuswamyFrom the Department of Clinical and Movement Neuroscience, (W.D.D., S.O., A.K.) Institute of Neurology, and Institute of Cognitive Neuroscience (L.C., S.O.), UCL, London, UK. a.kuppuswamy@ucl.ac.uk.

Funding

Wellcome Trust 202346/Z/16/Z
6 · The paper itself

Abstract

objectiveTo test the hypothesis that poststroke fatigue, a chronic, pathologic fatigue condition, is driven by altered effort perception.

methodsFifty-eight nondepressed, mildly impaired stroke survivors with varying severity of fatigue completed the study. Self-reported fatigue (trait and state), perceived effort (PE; explicit and implicit), and motor performance were measured in a handgrip task. Trait fatigue was measured with the Fatigue Severity Scale-7 and Neurologic Fatigue Index. State fatigue was measured with a visual analog scale (VAS). Length of hold at target force, overshoot above target force, and force variability in handgrip task were measures of motor performance. PE was measured with a VAS (explicit PE) and line length estimation, a novel implicit measure of PE.

resultsRegression analysis showed that 11.6% of variance in trait fatigue was explained by implicit PE (

conclusionTrait fatigue, but not state fatigue, correlating with measures of PE and motor performance, may suggest that altered perception may lead to high fatigue mediated by changes in motor performance. This finding furthers our mechanistic understanding of poststroke fatigue.

Indexed as

AgedDiagnostic Self EvaluationFatigueFemaleHandHumansMaleMiddle AgedPsychomotor PerformanceSeverity of Illness IndexStrokeSurvivors

Identifiers

PMID33067406
PMCPMC7836654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.