Evidence map›Paper›PMID 33067398›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Diatom modulation of select bacteria through use of two unique secondary metabolites.

Ahmed A Shibl, Ashley Isaac, Michael A Ochsenkühn, Anny Cárdenas, Cong Fei, Gregory Behringer, Marc Arnoux, Nizar Drou, Miraflor P Santos, Kristin C Gunsalus and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 187 citations in OpenAlex.

  1. Article
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  4. mBio · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Microbial Metabolism: Primary and Secondary Metabolites.Progress in molecular and subcellular biology · 2026
    Review
  10. Article
  11. Article
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  16. Review
  17. Iron limitation triggers roseoceramide biosynthesis and membrane remodeling in marine roseobacter.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 4 countries.

Ahmed A ShiblMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.ORCID 0000-0002-8147-8406
Ashley IsaacMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.ORCID 0000-0001-9859-4190
Michael A OchsenkühnMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.ORCID 0000-0003-0878-1756
Anny CárdenasDepartment of Biology, University of Konstanz, Konstanz 78467, Germany.
Cong FeiMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.
Gregory BehringerMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.
Marc ArnouxCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.ORCID 0000-0001-9387-8071
Nizar DrouCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.
Miraflor P SantosMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.
Kristin C GunsalusCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.ORCID 0000-0001-9769-4624
Christian R VoolstraDepartment of Biology, University of Konstanz, Konstanz 78467, Germany.ORCID 0000-0003-4555-3795
Shady A AminMarine Microbial Ecology Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates; samin@nyu.edu.ORCID 0000-0003-3780-8102
New York University Abu Dhabi · AEUniversity of Konstanz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unicellular eukaryotic phytoplankton, such as diatoms, rely on microbial communities for survival despite lacking specialized compartments to house microbiomes (e.g., animal gut). Microbial communities have been widely shown to benefit from diatom excretions that accumulate within the microenvironment surrounding phytoplankton cells, known as the phycosphere. However, mechanisms that enable diatoms and other unicellular eukaryotes to nurture specific microbiomes by fostering beneficial bacteria and repelling harmful ones are mostly unknown. We hypothesized that diatom exudates may tune microbial communities and employed an integrated multiomics approach using the ubiquitous diatom

Indexed as

Water MicrobiologyAnimalsBacteriaCinnamatesDepsidesDiatomsDicarboxylic AcidsGene Expression ProfilingMetabolomicsMetagenomeMetagenomicsMicrobiotaOceans and SeasPhytoplanktonRosmarinic AcidSecondary Metabolismazelaic acidCinnamatesDepsidesDicarboxylic AcidsRosmarinic Aciddiatomsmicrobiomesphycospherephytoplankton–bacteria interactionssecondary metabolism

Identifiers

PMID33067398
PMCPMC7959551
OpenAlexW3092862335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.