Evidence map›Paper›PMID 33067380›Full record

Observational studyScience immunology2020

A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses.

Victoria Stary, Ram Vinay Pandey, Johanna Strobl, Lisa Kleissl, Patrick Starlinger, David Pereyra, Wolfgang Weninger, Gottfried F Fischer, Christoph Bock, Matthias Farlik and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Science immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Reinvigorating COTL1Nature cell biology · 2026
    Article
  3. Article
  4. Resident CD49aScience advances · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. OMIP-098: A 26 parameter, 24 color flow cytometry panel for human memory NK cell phenotyping.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Natural killer cells in antiviral immunity.Nature reviews. Immunology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Victoria StaryDepartment of Visceral Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3854-9934
Ram Vinay PandeyDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Johanna StroblDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3606-2185
Lisa KleisslDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-8011-796X
Patrick StarlingerDepartment of Visceral Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
David PereyraDepartment of Visceral Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-6700-9163
Wolfgang WeningerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Gottfried F FischerDepartment of Blood Group Serology, University of Vienna, Vienna, Austria.ORCID 0000-0002-3442-3680
Christoph BockCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.ORCID 0000-0001-6091-3088
Matthias FarlikDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-0698-2992
Georg StaryDepartment of Dermatology, Medical University of Vienna, Vienna, Austria. georg.stary@meduniwien.ac.at.ORCID 0000-0003-1746-4250

Funding

Austrian Science Fund FWF P 30972
6 · The paper itself

Abstract

Adaptive features of natural killer (NK) cells have been reported in various species with different underlying mechanisms. It is unclear, however, which NK cell populations are capable of mounting antigen-specific recall responses and how such functions are regulated at the molecular level. Here, we identify and characterize a discrete population of CD49a

Indexed as

Adaptive ImmunityAdultAgedAged, 80 and overBiopsyCell Line, TumorCell SeparationDermatitis, ContactEpigenesis, GeneticFemaleFlow CytometryHumansIntegrin alpha1Killer Cells, NaturalLiverLymphocyte SubsetsIntegrin alpha1Nickel

Identifiers

PMID33067380
PMCPMC7615005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.