Evidence map›Paper›PMID 33067246›Full record

ArticleBMJ open diabetes research & care2020

tRNA methyltransferase 10 homologue A (

Hu Lin, Xuelian Zhou, Xuefeng Chen, Ke Huang, Wei Wu, Junfen Fu, Yangxi Li, Constantin Polychronakos, Guan-Ping Dong

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Human mutation · 2026
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  9. Article
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  11. Expanding the Phenotype ofJournal of clinical research in pediatric endocrinology · 2023
    Article
  12. Journal of clinical research in pediatric endocrinology · 2022
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Hu LinDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.ORCID 0000-0003-2253-7223
Xuelian ZhouDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.
Xuefeng ChenDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.
Ke HuangDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.
Wei WuDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.
Junfen FuDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China.
Yangxi LiThe Endocrine Genetics Laboratory, Department of Pediatrics, Research Institute of McGill University Health Centre, Montreal, Quebec, Canada.
Constantin PolychronakosThe Endocrine Genetics Laboratory, Department of Pediatrics, Research Institute of McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0002-7624-6635
Guan-Ping DongDepartment of Endocrinology, The Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang Province, China dgpxlx@zju.edu.cn.ORCID 0000-0001-6389-5719
Children's Hospital of Zhejiang University · CNMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLoss-of-function mutations in tRNA methyltransferase 10 homologue A ( RESEARCH DESIGN AND

methodsWe report a Chinese young patient who was diagnosed with diabetes mellitus as a result of a

resultsA homozygous mutation c.496-1G>A in

conclusionOur case is the first report in the Asian population. It adds to current knowledge of

Indexed as

Diabetes MellitusInsulin ResistanceMicrocephalyChildChinaHumansMethyltransferasesMutationtRNA MethyltransferasesMethyltransferasesTRMT10A protein, humantRNA Methyltransferasesinsulin resistance

Identifiers

PMID33067246
PMCPMC7569974
OpenAlexW3093308359

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.