ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2021
Neurobiological Markers of Resilience to Early-Life Adversity During Adolescence.
Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- The effects of childhood adversity: Two specific neural patterns.Neuroscience and biobehavioral reviews · 2025Pooled it
- The Transdiagnostic Origins of Anxiety and Depression During the Pediatric Period: Linking NIMH Research Domain Criteria (RDoC) Constructs to Ecological Systems.Development and psychopathology · 2021Pooled it
- A protocol for the Teen Bugs study: An integrative, multi-omics approach to understanding the role of the gut microbiome and mesocorticolimbic system in adolescent mental health following early adverse caregiving.Brain, behavior, & immunity - health · 2026Article
- Friends, family, and community influences on adolescent development: A review of impactful findings from the ABCD study®.Developmental cognitive neuroscience · 2026Article
- Persistent structural alteration of the extended limbic system in adolescents with childhood maltreatment.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Review
- Structural Brain Correlates of Multidomain Resilience Among Youth Exposed to Neighborhood Disadvantage.Biological psychiatry global open science · 2025Article
- Atypical Neural Activation During Emotional but Not Nonemotional Response Inhibition in Healthy Young People Exposed to Childhood Maltreatment and Peer Victimization.Biological psychiatry global open science · 2025Article
- The impact of grit on adolescent resilience in examining longitudinal mental health outcomes in peri-rural South Africa.Research square · 2025Article
- Investigative Approaches to Resilient Emotion Regulation Neurodevelopment in a South African Birth Cohort.Biological psychiatry global open science · 2025Article
- Early-life stress impairs acquisition and retrieval of fear memories: sex-effects, corticosterone modulation, and partial prevention by targeting glucocorticoid receptors at adolescent age.Neurobiology of stress · 2024Review
- Early life adversity impacts alterations in brain structure and food addiction in individuals with high BMI.Scientific reports · 2024Article
- A gut (microbiome) feeling about addiction: Interactions with stress and social systems.Neurobiology of stress · 2024Review
- Transcutaneous auricular vagus nerve stimulation ameliorates adolescent depressive- and anxiety-like behaviors via hippocampus glycolysis and inflammation response.CNS neuroscience & therapeutics · 2024Article
- Resilience following childhood adversity: The need for a heuristic multilevel dynamic framework.Neuroscience applied · 2024Article
- COVID-19-related stress exacerbates the effect of child maltreatment on negative affect via increased identity confusion during adolescence.Journal of adolescence · 2024Article
- Immediate and longer-term changes in mental health of children with parent-child separation experiences during the COVID-19 pandemic.Child and adolescent psychiatry and mental health · 2023Article
- Inhibitory control and mood in relation to psychological resilience: an ecological momentary assessment study.Scientific reports · 2023Article
- Psychological Resilience Interventions for Adolescents during the COVID-19 Pandemic.Behavioral sciences (Basel, Switzerland) · 2023Article
- Role of body mass index in the relationship between adverse childhood experiences, resilience, and mental health: a multivariate analysis.BMC psychiatry · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Early-life adversity (ELA) exposure (e.g., trauma, abuse, neglect, or institutional care) is a precursor to poor physical and mental health outcomes and is implicated in 30% of adult mental illness. In recent decades, ELA research has increasingly focused on characterizing factors that confer resilience to ELA and on identifying opportunities for intervention. In this review, we describe recent behavioral and neurobiological resilience work that suggests that adolescence (a period marked by heightened plasticity, development of key neurobiological circuitry, and sensitivity to the social environment) may be a particularly opportune moment for ELA intervention. We review intrapersonal factors associated with resilience that become increasingly important during adolescence (specifically, reward processing, affective learning, and self-regulation) and describe the contextual factors (family, peers, and broader social environment) that modulate them. In addition, we describe how the onset of puberty interacts with each of these factors, and we explore recent findings that point to possible "pubertal recalibration" of ELA exposure as an opportunity for intervention. We conclude by describing considerations and future directions for resilience research in adolescents, with a focus on understanding developmental trajectories using dimensional and holistic models of resilience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.