Evidence map›Paper›PMID 33067029›Full record

ArticleMedicina intensiva2020

Awake pronation with helmet continuous positive airway pressure for COVID-19 acute respiratory distress syndrome patients outside the ICU: A case series.

G Paternoster, C Sartini, E Pennacchio, F Lisanti, G Landoni, L Cabrini

Open access · greenAbstract read
In one paragraph

Article in Medicina intensiva, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

G PaternosterCardiovascular Anesthesia and ICU, San Carlos Regional Hospital (San Carlo Azienda Ospedaliera Regionale), Potenza, Italy.
C SartiniDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: sartini.chiara@hsr.it.
E PennacchioEmergency Medicine San Carlo Hospital San Carlos Regional Hospital (San Carlo Azienda Ospedaliera Regionale), Potenza, Italy.
F LisantiEmergency Medicine San Carlo Hospital San Carlos Regional Hospital (San Carlo Azienda Ospedaliera Regionale), Potenza, Italy.
G LandoniDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
L CabriniIntensive Care and Anesthesia Unit, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Ospedale San Carlo · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleOspedale di Circolo e Fondazione Macchi · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveContinuous positive airway pressure (CPAP) is an important therapeutic tool in COVID-19 acute respiratory distress syndrome (ARDS) since it improves oxygenation, reduces respiratory rate and can prevent intubation and intensive care unit (ICU) admission. CPAP during pronation has seldom been described and never during sedation.

designCase series.

settingHigh dependency unit of San Carlo University Hospital (Potenza, Italy). PATIENTS: Eleven consecutive patients with COVID-19 ARDS.

interventionHelmet CPAP in prone position after failing a CPAP trial in the supine position. MAIN VARIABLE OF INTEREST: Data collection at baseline and then after 24, 48 and 72h of pronation. We measured PaO

resultsPatients were treated with helmet CPAP for a mean±SD of 7±2.7 days. Prone positioning was feasible in all patients, but in 7 of them dexmedetomidine improved comfort. PaO

conclusionsHelmet CPAP during pronation was feasible and safe in COVID-19 ARDS managed outside the ICU and sedation with dexmedetomidine safely improved comfort. We recorded an increase in PaO

Indexed as

Acute respiratory failureARDSARFCascoCOVID-19CPAPDexmedetomidinaDexmedetomidineInsuficiencia respiratoria agudaNIVPandemiaPandemicPosición pronaPronaciónPronationProne positionSARS-CoV-2SARS-COV-2SDRASíndrome de dificultad respiratoria aguda

Identifiers

PMID33067029
PMCPMC7474866
OpenAlexW3083408173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.