Evidence map›Paper›PMID 33067013›Full record

ArticleClinical therapeutics2020

Caregivers' Willingness to Accept Expedited Vaccine Research During the COVID-19 Pandemic: A Cross-sectional Survey.

Ran D Goldman, Shashidhar R Marneni, Michelle Seiler, Julie C Brown, Eileen J Klein, Cristina Parra Cotanda, Renana Gelernter, Tyler D Yan, Julia Hoeffe, Adrienne L Davis and 10 more

Abstract read
In one paragraph

Article in Clinical therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
  10. Trust in scientists on COVID-19 vaccine hesitancy and vaccine intention in China and the US.International journal of disaster risk reduction : IJDRR · 2023
    Article
  11. Article
  12. Attitude of Parents of Children with Cerebral Palsy Towards COVID-19 Vaccination.International journal of environmental research and public health · 2023
    Article
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Ran D GoldmanThe Pediatric Research in Emergency Therapeutics Program, Division of Emergency Medicine, Department of Pediatrics, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada. Electronic address: rgoldman@cw.bc.ca.
Shashidhar R MarneniDepartment of Pediatric Emergency Medicine, Children's Medical Center of Dallas, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Michelle SeilerEmergency Department, University Children's Hospital Zurich, Zurich, Switzerland.
Julie C BrownSeattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
Eileen J KleinSeattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
Cristina Parra CotandaPediatric Emergency Department, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain.
Renana GelernterPediatric Emergency Medicine Unit, Shamir Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tyler D YanThe Pediatric Research in Emergency Therapeutics Program, Division of Emergency Medicine, Department of Pediatrics, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Julia HoeffeDivision of Pediatric Emergency Medicine, Inselspital University Hospital of Bern, Bern, Switzerland.
Adrienne L DavisDivision of Pediatric Emergency Medicine, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
Mark A GriffithsDivision of Pediatric Emergency Medicine, Children's Healthcare of Atlanta, Emory School of Medicine, Atlanta, GA, USA.
Jeanine E HallDivision of Emergency and Transport Medicine, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Gianluca GualcoPediatric Emergency Department, Pediatric Institute of Italian Part of Switzerland, Ticino, Switzerland.
Ahmed MaterDivision of Pediatric Emergency Medicine, Jim Pattison Children's Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Sergio ManzanoDepartment of Pediatric Emergency Medicine, Geneva Children's Hospital, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Graham C ThompsonDivision of Pediatrics and Emergency Medicine, Alberta Children's Hospital and University of Calgary, Calgary, Alberta, Canada.
Sara AhmedDepartment of Emergency Medicine, Mary Bridge Children's Hospital, Tacoma, WA, USA.
Samina AliDepartment of Pediatrics, Faculty of Medicine and Dentistry, Women and Children's Health Research Institute, University of Alberta, Edmonton, Alberta, Canada.
Naoki ShimizuDepartment of Pediatrics, St. Marianna University School of Medicine, Kawasaki, Japan.
International COVID-19 Parental Attitude Study (COVIPAS) Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study determined the predictors of caregivers' willingness to accept an accelerated regulatory process for the development of vaccines against coronavirus disease 2019 (COVID-19).

methodsAn international cross-sectional survey was administered to 2557 caregivers of children in 17 pediatric emergency departments (EDs) across 6 countries from March 26, 2020, to June 30, 2020. Caregivers were asked to select 1 of 4 choices with which they most agreed regarding a proposed COVID-19 vaccine-approval process, in addition to questions regarding demographic characteristics, the ED visit, and attitudes about COVID-19. Univariate analyses were conducted using the Mann-Whitney U test for comparing non-normally distributed continuous variables, an independent t test for comparing normally distributed continuous variables, and a χ

findingsAlmost half (1101/2557; 43%) of caregivers reported that they were willing to accept less rigorous testing and postresearch approval of a new COVID-19 vaccine. Independent factors associated with caregivers' willingness to accept expedited COVID-19 vaccine research included having children who were up to date on the vaccination schedule (odds ratio [OR] = 1.72; 95% CI, 1.29-2.31), caregivers' concern about having had COVID-19 themselves at the time of survey completion in the ED (OR = 1.1; 95% CI, 1.05-1.16), and caregivers' intent to have their children vaccinated against COVID-19 if a vaccine were to become available (OR = 1.84; 95% CI, 1.54-2.21). Compared with fathers, mothers completing the survey were less likely to approve of changes in the vaccine-development process (OR = 0.641; 95% CI, 0.529-0.775). IMPLICATIONS: Less than half of caregivers in this worldwide sample were willing to accept abbreviated COVID-19 vaccine testing. As a part of an effort to increase acceptance and uptake of a new vaccine, especially in order to protect children, public health strategies and individual providers should understand caregivers' attitudes toward the approval of a vaccine and consult them appropriately.

Indexed as

CaregiversCOVID-19COVID-19 VaccinesHealth Knowledge, Attitudes, PracticeBiomedical ResearchCross-Sectional StudiesHumansPatient Acceptance of Health CareSARS-CoV-2Time FactorsCOVID-19 VaccinesCOVID-19drug approvalparental attitudesvaccine

Identifiers

PMID33067013
PMCPMC7532744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.