ReviewActa histochemica2020
Marking vertebrates langerhans cells, from fish to mammals.
Review in Acta histochemica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Allies in the Skin Defense System: The Role of Thread Cells in the Evolution of Hagfish (Myxiniformes).Biology · 2025Article
- Comprehensive analysis of transcriptome and pathway interactions in periodontitis.Journal of applied oral science : revista FOB · 2025Article
- Immunohistochemical Characterization of Langerhans Cells in the Skin of Three Amphibian Species.Biology · 2024Article
- Fishing Innate Immune System Properties through the Transcriptomic Single-Cell Data ofBiology · 2023Review
- Coelomocytes of the Oligochaeta earthworm Lumbricus terrestris (Linnaeus, 1758) as evolutionary key of defense: a morphological study.Zoological letters · 2023Article
- Immunohistochemistry of the Gut-Associated Lymphoid Tissue (GALT) in African Bonytongue (International journal of molecular sciences · 2023Article
- Expression of Antimicrobic Peptide Piscidin1 in Gills Mast Cells of Giant MudskipperInternational journal of molecular sciences · 2022Article
- Immunogenicity, effectiveness, safety and psychological impact of COVID-19 mRNA vaccines.Human immunology · 2022Review
- Article
- Localization of vasoactive intestinal peptide and toll-like receptor 2 immunoreactive cells in endostyle of urochordate Styela plicata (Lesueur, 1823).Microscopy research and technique · 2022Article
- Immune System and Psychological State of Pregnant Women during COVID-19 Pandemic: Are Micronutrients Able to Support Pregnancy?Nutrients · 2022Review
- Review
- Article
- Article
- Relationship between Immune Cells, Depression, Stress, and Psoriasis: Could the Use of Natural Products Be Helpful?Molecules (Basel, Switzerland) · 2022Review
- Resveratrol and Immune Cells: A Link to Improve Human Health.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Langerhans cells (LCs) are specialized dendritic cells (DCs) that play a defense role in recognizing foreign antigens, in tissue where antigenic exposures occur, as in the skin and mucous membranes. LCs are able to continuously move within the tissues thanks to dendritic contraction and distension performing their surveillance and/or phagocytosis role. These cells are characterized by the presence of Birbeck granules in their cytoplasm, involved in endocytosis. LCs have been characterized in several classes of vertebrates, from fish to mammals using different histological and molecular techniques. The aim of the present review is to define the state of art and the need of information about immunohistochemical markers of LCs in different classes of vertebrates. The most used immunohistochemical (IHC) markers are Langerin/CD207, CD1a, S-100 and TLR. These IHC markers are described in relation to their finding in different vertebrate classes with phylogenetical considerations. Among the four markers, Langerin/CD207 and TLR have the widest spectrum of cross reactivity in LCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.