Evidence map›Paper›PMID 33066731›Full record

ArticleBMC cardiovascular disorders2020

Epinephrine soaked tampons induced transient acute dilated cardiomyopathy during FESS procedure.

Sari Naddaf, Scott Ehrenberg, Rony Hakim, Muhamad Mahamid, Yoav Turgeman, Ofir Koren

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sari NaddafBruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Scott EhrenbergBruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Rony HakimDepartment of Anaesthesia, Emek Medical Center, Afula, Israel.
Muhamad MahamidHeart Institute, Emek Medical Center, Afula, Israel.
Yoav TurgemanBruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Ofir KorenBruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Drkorenofir@gmail.com.ORCID 0000-0002-8666-8276
Emek Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpinephrine, in all modes of use, may pose a wide range of cardiotoxic events, ranging from sinus tachycardia to heart failure, life threatening arrhythmias, and even death. Because of daily and extensive use of epinephrine, these unusual and rare events tend to be forgotten by physicians. We present a case of dilated cardiomyopathy that developed following routine use of epinephrine-impregnated tampons during function endoscopic sinus (FESS) surgery. CASE PRESENTATION: A healthy, 24-year-old man with no family history of heart disease has undergone elective surgery under general anesthesia to repair the paranasal sinuses using endoscopic approach. During surgery, soon after being treated with 1: 1000 diluted epinephrine-soaked tampons, an hypertensive crisis was noticed followed by pulseless electrical activity. An extensive examination led to the diagnosis of non-ischemic dilated cardiomyopathy. After several days of heart failure medical therapy, complete resolution of all structural and functional changes was achieved.

conclusionIn our case, we present an unusual and rare event of acute dilated cardiomyopathy following the use of epinephrine-soaked tampons during elective FESS surgery. A prompt response was observed after several days of heart failure treatment. Awareness of the epinephrine cardiotoxic potential even in the form of soaked tampons is essential for proper diagnosis and prompt treatment.

Indexed as

EndoscopyNasal Surgical ProceduresAcute DiseaseAdrenergic AgonistsCardiomyopathy, DilatedCardiotoxicityEpinephrineHumansMaleParanasal SinusesTampons, SurgicalTreatment OutcomeYoung AdultAdrenergic AgonistsEpinephrineDilated cardiomyopathyEpinephrineFESSHeart failureSurgery

Identifiers

PMID33066731
PMCPMC7566064
OpenAlexW3092663731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.