ArticleJournal of neurotrauma2021
Correlating Tissue Mechanics and Spinal Cord Injury: Patient-Specific Finite Element Models of Unilateral Cervical Contusion Spinal Cord Injury in Non-Human Primates.
Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Intramedullary Strain During Neck Extension is Associated with Microstructural Spinal Cord Injury in Degenerative Cervical Myelopathy.Annals of biomedical engineering · 2026Article
- Article
- Intraoperative elastography and spinal surgery: a systematic review of current and future applications in clinical and preclinical models.The ultrasound journal · 2025Review
- Finite Element Analysis for Degenerative Cervical Myelopathy: Scoping Review of the Current Findings and Design Approaches, Including Recommendations on the Choice of Material Properties.JMIR biomedical engineering · 2024Article
- Biomechanical analysis of spinal cord injury during scoliosis correction surgery.Frontiers in bioengineering and biotechnology · 2024Article
- The biomechanical implications of neck position in cervical contusion animal models of SCI.Frontiers in neurology · 2023Review
- Effects of cervical rotatory manipulation on the cervical spinal cord complex with ossification of the posterior longitudinal ligament in the vertebral canal: A finite element study.Frontiers in bioengineering and biotechnology · 2023Article
- Effect of Impact Parameters on a Unilateral Contusion Model of Spinal Cord Injury in a Virtual Population of Non-Human Primates.Neurotrauma reports · 2023Article
- Effect of mechanical stimulation on tissue heterotopic ossification: anFrontiers in physiology · 2023Article
- Tensile properties of human spinal dura mater and pericranium.Journal of materials science. Materials in medicine · 2022Article
- Article
- Effects of cervical rotatory manipulation on the cervical spinal cord: a finite element study.Journal of orthopaedic surgery and research · 2021Article
- Intubation Biomechanics: Clinical Implications of Computational Modeling of Intervertebral Motion and Spinal Cord Strain during Tracheal Intubation in an Intact Cervical Spine.Anesthesiology · 2021Article
- A Hyper-Viscoelastic Continuum-Level Finite Element Model of the Spinal Cord Assessed for Transverse Indentation and Impact Loading.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Non-human primate (NHP) models are the closest approximation of human spinal cord injury (SCI) available for pre-clinical trials. The NHP models, however, include broader morphological variability that can confound experimental outcomes. We developed subject-specific finite element (FE) models to quantify the relationship between impact mechanics and SCI, including the correlations between FE outcomes and tissue damage. Subject-specific models of cervical unilateral contusion SCI were generated from pre-injury MRIs of six NHPs. Stress and strain outcomes were compared with lesion histology using logit analysis. A parallel generic model was constructed to compare the outcomes of subject-specific and generic models. The FE outcomes were correlated more strongly with gray matter damage (0.29 < R
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.