Evidence map›Paper›PMID 33066435›Full record

ReviewCells2020

Neurological Disturbances of Ciguatera Poisoning: Clinical Features and Pathophysiological Basis.

Killian L'Herondelle, Matthieu Talagas, Olivier Mignen, Laurent Misery, Raphaele Le Garrec

Abstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Poison Apple-like Fruit Ingestion: A Case Report and Review of Manchineel Fruit Toxicity.International journal of environmental research and public health · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Toxins · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases:International journal of molecular sciences · 2021
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Killian L'HerondelleUniversity of Brest, School of Medicine, Laboratoire Interactions Epithéliums-Neurones (Univ Brest, LIEN), F-29200 Brest, France.
Matthieu TalagasUniversity of Brest, School of Medicine, Laboratoire Interactions Epithéliums-Neurones (Univ Brest, LIEN), F-29200 Brest, France.ORCID 0000-0001-6769-3364
Olivier MignenUniversity of Brest, School of Medicine, INSERM U1227, Lymphocytes B et auto-immunité, F-29200 Brest, France.
Laurent MiseryUniversity of Brest, School of Medicine, Laboratoire Interactions Epithéliums-Neurones (Univ Brest, LIEN), F-29200 Brest, France.ORCID 0000-0001-8088-7059
Raphaele Le GarrecUniversity of Brest, School of Medicine, Laboratoire Interactions Epithéliums-Neurones (Univ Brest, LIEN), F-29200 Brest, France.ORCID 0000-0002-0269-9076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciguatera fish poisoning (CFP), the most prevalent seafood poisoning worldwide, is caused by the consumption of tropical and subtropical fish contaminated with potent neurotoxins called ciguatoxins (CTXs). Ciguatera is a complex clinical syndrome in which peripheral neurological signs predominate in the acute phase of the intoxication but also persist or reoccur long afterward. Their recognition is of particular importance in establishing the diagnosis, which is clinically-based and can be a challenge for physicians unfamiliar with CFP. To date, no specific treatment exists. Physiopathologically, the primary targets of CTXs are well identified, as are the secondary events that may contribute to CFP symptomatology. This review describes the clinical features, focusing on the sensory disturbances, and then reports on the neuronal targets and effects of CTXs, as well as the neurophysiological and histological studies that have contributed to existing knowledge of CFP neuropathophysiology at the molecular, neurocellular and nerve levels.

Indexed as

Action PotentialsAnimalsCiguatera PoisoningCiguatoxinsDiagnostic ErrorsHumansNervous System DiseasesPrevalenceCiguatoxinsciguateraciguatoxinneurologicalpathophysiologysensory

Identifiers

PMID33066435
PMCPMC7602189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.