Evidence map›Paper›PMID 33066403›Full record

ArticleInternational journal of molecular sciences2020

In Vivo Modulation of Angiogenesis and Immune Response on a Collagen Matrix via Extracorporeal Shockwaves.

Diana Heimes, Nadine Wiesmann, Jonas Eckrich, Juergen Brieger, Stefan Mattyasovszky, Peter Proff, Manuel Weber, James Deschner, Bilal Al-Nawas, Peer W Kämmerer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Extracorporeal shockwave therapy (ESWT) in hand surgery].Orthopadie (Heidelberg, Germany) · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Shock Waves for Hair Growth and Regeneration in Patients With Female Pattern Hair Loss.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. APL bioengineering · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Diana HeimesDepartment of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Nadine WiesmannDepartment of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.ORCID 0000-0001-5661-6953
Jonas EckrichMolecular Tumor Biology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, 55131 Mainz, Germany.
Juergen BriegerMolecular Tumor Biology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, 55131 Mainz, Germany.
Stefan MattyasovszkyDepartment of Orthopedics and Traumatology, University Medical Center of the Johannes Gutenberg University of Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.
Peter ProffDepartment of Orthodontics, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Manuel WeberDepartment of Oral and Maxillofacial Surgery, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Augustusplatz 2, 55131 Mainz, Germany.
Bilal Al-NawasDepartment of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Peer W KämmererDepartment of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.ORCID 0000-0002-1671-3764
Johannes Gutenberg University Mainz · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effective management of tissue integration and immunological responses to transplants decisively co-determines the success of soft and hard tissue reconstruction. The aim of this in vivo study was to evaluate the eligibility of extracorporeal shock wave therapy (ESWT) with respect to its ability to modulate angiogenesis and immune response to a collagen matrix (CM) for tissue engineering in the chorioallantoic membrane (CAM) assay, which is performed with fertilized chicken eggs. CM were placed on the CAM on embryonic development day (EDD) 7; at EDD-10, ESWT was conducted at 0.12 mJ/mm

Indexed as

Neovascularization, PhysiologicAnimalsAvian ProteinsChick EmbryoChorioallantoic MembraneCollagenExtracorporeal Shockwave TherapyHypoxia-Inducible Factor 1, alpha SubunitMatrix MetalloproteinasesNitric Oxide Synthase Type IITissue EngineeringTissue ScaffoldsVascular Endothelial Growth Factor AAvian ProteinsCollagenHypoxia-Inducible Factor 1, alpha SubunitMatrix MetalloproteinasesNitric Oxide Synthase Type IIVascular Endothelial Growth Factor Aangiogenesischorioallantoic membrane assaycollagen matrixextracorporeal shockwave therapymacrophage responsematrix metalloproteasesmucoderm®oral inflammationvascular endothelial growth factor

Identifiers

PMID33066403
PMCPMC7589066
OpenAlexW3092656111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.