Evidence map›Paper›PMID 33066333›Full record

ReviewMolecules (Basel, Switzerland)2020

Importance of Fluorine in Benzazole Compounds.

Thuraya Al-Harthy, Wajdi Zoghaib, Raid Abdel-Jalil

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. In Vitro Anti-Molecules (Basel, Switzerland) · 2021
    Article
  13. Design and Synthesis of Fluoro Analogues of Vitamin D.International journal of molecular sciences · 2021
    Review
  14. δ-Lactones-A New Class of Compounds That Are Toxic toMaterials (Basel, Switzerland) · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Thuraya Al-HarthyDepartment of Basic Sciences, College of Applied and Health Sciences, A'Sharqiyah University, Ibra 400, Oman.ORCID 0000-0002-8009-7804
Wajdi ZoghaibChemistry Department, College of Science, Sultan Qaboos University, Al-Khod, Muscat 123, Oman.
Raid Abdel-JalilChemistry Department, College of Science, Sultan Qaboos University, Al-Khod, Muscat 123, Oman.ORCID 0000-0002-1743-4521
Sultan Qaboos University · OMShaqra University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorine-containing heterocycles continue to receive considerable attention due to their unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules imparts a significant enhancement their biological activities compared to non-fluorinated molecules. In this short review, we will highlight the importance of incorporating fluorine as a basic appendage in benzothiazole and benzimidazole skeletons. The chemistry and pharmacological activities of heterocycles containing fluorine during the past years are compiled and discussed.

Indexed as

Structure-Activity RelationshipAgammaglobulinaemia Tyrosine KinaseBenzimidazolesBenzothiazolesChemistry, PharmaceuticalDrug DesignEnzyme InhibitorsFluorineHeterocyclic Compounds, 2-RingHumansAgammaglobulinaemia Tyrosine KinasebenzimidazoleBenzimidazolesbenzothiazoleBenzothiazolesBTK protein, humanEnzyme InhibitorsFluorineHeterocyclic Compounds, 2-Ringbenzazolesbenzimidazolesbenzothiazolesbenzoxazolebiological activitiesfluorine

Identifiers

PMID33066333
PMCPMC7587361
OpenAlexW3092885465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.