A Red Fluorescent Protein-Based Probe for Detection of Intracellular Reactive Sulfane Sulfur.

Zimai Li, Qingda Wang, Yongzhen Xia, Luying Xun, Huaiwei Liu

Open access · goldAbstract read

In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 36% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

Sulfane Sulfur Is a Strong Inducer of the Multiple Antibiotic Resistance Regulator MarR inAntioxidants (Basel, Switzerland) · 2021
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Zimai LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.

Qingda WangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.

Yongzhen XiaState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0001-9950-1910

Luying XunState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-5770-9016

Huaiwei LiuState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-0483-5318

Shandong University · CN

Funding

the National Key Research and Development Program of China 2016YFA0601103, 91951202, 2018YFA0901200

6 · The paper itself

Abstract

Reactive sulfane sulfur, including persulfide and polysulfide, is a type of regular cellular component, playing an antioxidant role. Its function may be organelle-dependent; however, the shortage of probes for detecting organellar reactive sulfane sulfur has hindered further investigation. Herein, we reported a red fluorescent protein (mCherry)-based probe for specifically detecting intracellular reactive sulfane sulfur. By mutating two amino acid residues of mCherry (A150 and S151) to cysteine residues, we constructed a mCherry mutant, which reacted with reactive sulfane sulfur to form an intramolecular -S

Indexed as

antioxidationmCherrymitochondriaSaccharomyces cerevisiaesulfane sulfur

Identifiers

PMID33066305

DOI10.3390/antiox9100985

PMCPMC7602056

OpenAlexW3093081405

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.