Evidence map›Paper›PMID 33066298›Full record

ArticleMolecules (Basel, Switzerland)2020

Pimarane Diterpenoids from the Seeds of

Yunshao Xu, Zheling Feng, Tian Zhang, Peng Lv, Jun Cao, Dan Li, Cheng Peng, Ligen Lin

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunshao XuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
Zheling FengState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
Tian ZhangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
Peng LvState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
Jun CaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
Dan LiState Key Laboratory of Southwestern Characteristic Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Cheng PengState Key Laboratory of Southwestern Characteristic Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Ligen LinState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.ORCID 0000-0002-6799-5327

Funding

National Natural Science Foundation of China 81872754Science and Technology Development Fund, Macao S.A.R FDCT 0031/2019/A1University of Macau MYRG2017-00109-ICMS
6 · The paper itself

Abstract

Protein-tyrosine phosphatase 1B (PTP1B) has been considered as a promising target for treating insulin resistance. In searching for naturally occurring PTB1B antagonists, two new pimarane diterpenoids, named 2α-hydroxy-7-oxo-pimara-8(9),15-diene (

Indexed as

AbietanesAnimalsCaesalpiniaCircular DichroismDose-Response Relationship, DrugDrug Evaluation, PreclinicalEnzyme InhibitorsGlucoseInsulinMagnetic Resonance SpectroscopyMiceMolecular StructureMuscle Fibers, SkeletalProtein Tyrosine Phosphatase, Non-Receptor Type 1SeedsSpectrometry, Mass, Electrospray IonizationAbietanesEnzyme InhibitorsGlucoseInsulinProtein Tyrosine Phosphatase, Non-Receptor Type 1C2C12 myotubesCaesalpinia minaxglucose uptakepimarane diterpenoidsPTP1B

Identifiers

PMID33066298
PMCPMC7587383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.