Evidence map›Paper›PMID 33066271›Full record

ArticleInternational journal of molecular sciences2020

Proposing Urothelial and Muscle In Vitro Cell Models as a Novel Approach for Assessment of Long-Term Toxicity of Nanoparticles.

Matej Skočaj, Maruša Bizjak, Klemen Strojan, Jasna Lojk, Mateja Erdani Kreft, Katarina Miš, Sergej Pirkmajer, Vladimir Boštjan Bregar, Peter Veranič, Mojca Pavlin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Matej SkočajGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.ORCID 0000-0002-5975-1568
Maruša BizjakGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Klemen StrojanGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Jasna LojkGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Mateja Erdani KreftInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI -1000 Ljubljana, Slovenia.ORCID 0000-0001-6486-165X
Katarina MišInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Sergej PirkmajerInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Vladimir Boštjan BregarGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Peter VeraničInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI -1000 Ljubljana, Slovenia.
Mojca PavlinGroup for nano and biotechnological applications, Faculty of Electrical Engineering, University of Ljubljana, SI -1000 Ljubljana, Slovenia.ORCID 0000-0001-5477-7833
University of Ljubljana · SI

Funding

Slovenian Research Agency J2-6758, J3-6794, J7-7424, J3-7494, P1-0055, P3-0108, IP-0510Slovenian Research Agency MB was also supported by the Slovenian Research Agency young researchers program. SP and KM are supported also by the Slovenian Research Agency grants P3-0043, J7-7138 and J7-8276, JL was also supported by the Slovenian Research Agency grant Z4-8229.
6 · The paper itself

Abstract

Many studies evaluated the short-term in vitro toxicity of nanoparticles (NPs); however, long-term effects are still not adequately understood. Here, we investigated the potential toxic effects of biomedical (polyacrylic acid and polyethylenimine coated magnetic NPs) and two industrial (SiO

Indexed as

AnimalsCell LineCells, CulturedCell SurvivalEpithelial CellsMuscle CellsNanoparticlesNF-E2-Related Factor 2PolyestersRatsReactive Oxygen SpeciesSwineTitaniumToxicity TestsUrotheliumNfe2l2 protein, ratNF-E2-Related Factor 2Polyesterspoly(lactide)Reactive Oxygen SpeciesTitaniumtitanium dioxidecell signalingdifferentiationin vitro L6 rat skeletal muscle cell linenanotoxicologyROSurothelium in vitro

Identifiers

PMID33066271
PMCPMC7589566
OpenAlexW3092679437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.