Evidence map›Paper›PMID 33066266›Full record

ArticleInternational journal of molecular sciences2020

Vitamin D Status Modulates Inflammatory Response in HIV+ Subjects: Evidence for Involvement of Autophagy and TG2 Expression in PBMC.

Monica Currò, Giuseppa Visalli, Giovanni Francesco Pellicanò, Nadia Ferlazzo, Maria Giovanna Costanzo, Flavia D'Andrea, Daniela Caccamo, Giuseppe Nunnari, Riccardo Ientile

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Monica CurròDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-8852-7023
Giuseppa VisalliDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-9072-1148
Giovanni Francesco PellicanòUnit of Infectious Diseases, Department of Human Pathology of Adult and Childhood "Gaetano Barresi", University of Messina, 98125 Messina, Italy.ORCID 0000-0002-9640-8742
Nadia FerlazzoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.
Maria Giovanna CostanzoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.
Flavia D'AndreaUnit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Daniela CaccamoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-8593-9495
Giuseppe NunnariUnit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Riccardo IentileDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conflicting results on the involvement of vitamin D deficiency in inflammatory and immune response in HIV+ subjects are reported. We aimed to characterize the possible influence of vitamin D status on changes in expression of tissue transglutaminase gene (TGM2) and other genes involved in inflammatory response and autophagy in peripheral blood mononuclear cells (PBMC) from HIV+ subjects. HIV+ subjects (

Indexed as

Autophagy25-Hydroxyvitamin D3 1-alpha-HydroxylaseAdultAutophagy-Related Protein 5Beclin-1FemaleGTP-Binding ProteinsHIV InfectionsHumansInterferon-gammaMaleMicrotubule-Associated ProteinsMiddle AgedMonocytesProtein Glutamine gamma Glutamyltransferase 2Transglutaminases25-Hydroxyvitamin D3 1-alpha-HydroxylaseATG5 protein, humanAutophagy-Related Protein 5Beclin-1BECN1 protein, humanCYP27B1 protein, humanGTP-Binding ProteinsInterferon-gammaMAP1LC3A protein, humanMicrotubule-Associated ProteinsProtein Glutamine gamma Glutamyltransferase 2TGM2 protein, humanTransglutaminasesTumor Necrosis Factor-alphaVitamin DautophagycytokinesHIVinflammationperipheral blood mononuclear cellstissue transglutaminasevitamin D

Identifiers

PMID33066266
PMCPMC7588966
OpenAlexW3092846917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.