Evidence map›Paper›PMID 33066260›Full record

ArticleCancers2020

High PD-L1/CD274 Expression of Monocytes and Blood Dendritic Cells Is a Risk Factor in Lung Cancer Patients Undergoing Treatment with PD1 Inhibitor Therapy.

Dagmar Riemann, Wolfgang Schütte, Steffi Turzer, Barbara Seliger, Miriam Möller

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
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  8. Review
  9. Article
  10. Association betweenCancers · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Monocyte programming by cancer therapy.Frontiers in immunology · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dagmar RiemannInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, 06112 Halle, Germany.
Wolfgang SchütteClinic of Internal Medicine, Hospital Martha-Maria Halle-Dölau, 06120 Halle, Germany.
Steffi TurzerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, 06112 Halle, Germany.
Barbara SeligerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, 06112 Halle, Germany.
Miriam MöllerClinic of Internal Medicine, Hospital Martha-Maria Halle-Dölau, 06120 Halle, Germany.
Martin Luther University Halle-Wittenberg · DEMartha-Maria Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the expression of the coinhibitory molecule PD-L1/CD274 in monocytes and dendritic cells (DC) in the blood of lung cancer patients undergoing PD1 inhibitor therapy and to correlate data with patient's outcome. PD-L1/CD274 expression of monocytes, CD1c

Indexed as

blood monocytesCD16+ monocytesdendritic cellsflow cytometryimmune monitoringlung cancerPD1 inhibitor therapyPD-L1/CD274survival analysis

Identifiers

PMID33066260
PMCPMC7602055
OpenAlexW3092987674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.