Evidence map›Paper›PMID 33066249›Full record

ArticleCells2020

The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells.

Huan-I Jen, Zih-You Lin, Jin-Xun Guo, Cheng-I Lee

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Effect of Octapeptide Repeats on Prion Folding and Misfolding.International journal of molecular sciences · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huan-I JenDepartment of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Zih-You LinDepartment of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Jin-Xun GuoDepartment of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Cheng-I LeeDepartment of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.ORCID 0000-0002-3614-9195
National Chung Cheng University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transmissible spongiform encephalopathies (TSEs) are epidemic neurodegenerative diseases caused by prion proteins; in particular, they are induced by misfolded prion proteins (PrP

Indexed as

AnimalsCations, DivalentCell LineChelating AgentsCytokinesInflammation MediatorsInterleukin-1betaMiceMicrogliaNF-KappaB Inhibitor alphaNLR Family, Pyrin Domain-Containing 3 ProteinPeptidesPrionsReactive Oxygen SpeciesRepetitive Sequences, Amino AcidRNA, MessengerCations, DivalentChelating AgentsCytokinesInflammation MediatorsInterleukin-1betaNF-KappaB Inhibitor alphaNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousePeptidesPrionsReactive Oxygen SpeciesRNA, MessengerinflammationmicrogliaNLRP3 inflammasomeprion

Identifiers

PMID33066249
PMCPMC7602007
OpenAlexW3093263745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.