Evidence map›Paper›PMID 33066194›Full record

ArticleMolecules (Basel, Switzerland)2020

Design and Synthesis of Helical

Atsushi Ueda, Mei Higuchi, Kazuki Sato, Tomohiro Umeno, Masakazu Tanaka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. New Advances in Short Peptides: Looking Forward.Molecules (Basel, Switzerland) · 2022
    Article
  3. Advances in Research of Short Peptides.Molecules (Basel, Switzerland) · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Atsushi UedaGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Mei HiguchiGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Kazuki SatoGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Tomohiro UmenoGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Masakazu TanakaGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Nagasaki University · JP

Funding

Japan Society for the Promotion of Science JP17H03998Japan Society for the Promotion of Science JP18K14870Japan Society for the Promotion of Science JP20K06967Shionogi Award in Synthetic Organic Chemistry, Japan n/aUbe Industries Foundation n/a
6 · The paper itself

Abstract

We designed and synthesized helical short oligopeptides with an L-proline on the N-terminus and hydrocarbon stapling on the side chain. Side-chain stapling is a frequently used method for the development of biologically active peptides. Side-chain stapling can stabilize the secondary structures of peptides, and, therefore, stapled peptides may be applicable to peptide-based organocatalysts. Olefin-tethered

Indexed as

AlkenesCatalysisCircular DichroismHydrocarbonsIndolesOligopeptidesProlineProtein ConformationProtein EngineeringStructure-Activity Relationship1-methylindoleAlkenesHydrocarbonsIndolesOligopeptidesProlinehelixhydrocarbon staplingL-prolineMichael additionorganocatalystpeptidering-closing metathesis

Identifiers

PMID33066194
PMCPMC7594088
OpenAlexW3093141555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.