Evidence map›Paper›PMID 33066173›Full record

ArticleToxins2020

Prevalent Human Gut Bacteria Hydrolyse and Metabolise Important Food-Derived Mycotoxins and Masked Mycotoxins.

Noshin Daud, Valerie Currie, Gary Duncan, Freda Farquharson, Tomoya Yoshinari, Petra Louis, Silvia Gratz

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Toxins · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. The intestinal microbiota as mediators between dietary contaminants and host health.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Noshin DaudRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Valerie CurrieRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.ORCID 0000-0003-2842-6479
Gary DuncanRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Freda FarquharsonRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Tomoya YoshinariDivision of Microbiology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-9501, Japan.
Petra LouisRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Silvia GratzRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
University of Aberdeen · GBNational Institute of Health Sciences · JP

Funding

Scottish Government Rural, and Environment Science, and Analytical Services Division (RESAS) RG13487-22
6 · The paper itself

Abstract

Mycotoxins are important food contaminants that commonly co-occur with modified mycotoxins such as mycotoxin-glucosides in contaminated cereal grains. These masked mycotoxins are less toxic, but their breakdown and release of unconjugated mycotoxins has been shown by mixed gut microbiota of humans and animals. The role of different bacteria in hydrolysing mycotoxin-glucosides is unknown, and this study therefore investigated fourteen strains of human gut bacteria for their ability to break down masked mycotoxins. Individual bacterial strains were incubated anaerobically with masked mycotoxins (deoxynivalenol-3-β-glucoside, DON-Glc; nivalenol-3-β-glucoside, NIV-Glc; HT-2-β-glucoside, HT-2-Glc; diacetoxyscirpenol-α-glucoside, DAS-Glc), or unconjugated mycotoxins (DON, NIV, HT-2, T-2, and DAS) for up to 48 h. Bacterial growth, hydrolysis of mycotoxin-glucosides and further metabolism of mycotoxins were assessed. We found no impact of any mycotoxin on bacterial growth. We have demonstrated that

Indexed as

Gastrointestinal MicrobiomeAcetylationBacteriaBacterial ProteinsFood MicrobiologyGlucosidesHumansHydrolysisIntestinesMycotoxinsRisk AssessmentSubstrate SpecificityTime FactorsTrichothecenesBacterial ProteinsGlucosidesMycotoxinsTrichothecenesde-acetylationgut microbiotamicrobiomemycotoxin-glucosidesreleasetrichothecenes

Identifiers

PMID33066173
PMCPMC7601956
OpenAlexW3092980456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.