Evidence map›Paper›PMID 33066136›Full record

ArticleMicroorganisms2020

Clinical, Epidemiological, and Geospatial Characteristics of Patients Infected with Hepatitis C Virus Treated with Second-Generation Direct-Action Antivirals in a Reference Center in a Mesoregion of São Paulo State, Brazil.

Danilo Zangirolami Pena, Murilo Fernandes Anadão, Edilson Ferreira Flores, Mayara Namimatsu Okada, Alexandre Martins Portelinha Filho, Rodrigo Sala Ferro, Luiz Euribel Prestes-Carneiro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Danilo Zangirolami PenaInfectious Diseases Outpatient Clinic, Oeste Paulista University, Presidente Prudente 19050-920, São Paulo, Brazil.
Murilo Fernandes AnadãoInfectious Diseases Outpatient Clinic, Oeste Paulista University, Presidente Prudente 19050-920, São Paulo, Brazil.
Edilson Ferreira FloresStatistics Department, School of Sciences and Technology, São Paulo State University, Presidente Prudente 19060-900, São Paulo, Brazil.
Mayara Namimatsu OkadaPharmacy of the Outpatient Medical Specialties of Presidente Prudente, Presidente Prudente 19050-680, São Paulo, Brazil.
Alexandre Martins Portelinha FilhoInfectious Diseases Outpatient Clinic, Oeste Paulista University, Presidente Prudente 19050-920, São Paulo, Brazil.
Rodrigo Sala FerroInfectious Diseases Outpatient Clinic, Oeste Paulista University, Presidente Prudente 19050-920, São Paulo, Brazil.
Luiz Euribel Prestes-CarneiroInfectious Diseases Outpatient Clinic, Oeste Paulista University, Presidente Prudente 19050-920, São Paulo, Brazil.
Universidade do Oeste Paulista · BRHospital Regional de Presidente Prudente · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis virus infection is a major public health problem worldwide. Currently, Brazil has almost 700,000 cases. The Brazilian Unified Health System (SUS) provides therapeutic regimens for people infected with hepatitis C virus (HCV). We determined the clinical, laboratory, epidemiologic, and geospatial characteristics of patients infected with HCV treated with second-generation direct-action antivirals (DAAs) in a hospital reference center in São Paulo state, Brazil, using data from file records. A map was constructed using a geographic information system. From 2015 to 2018, 197 individuals received second-generation DAAs (mean age, 57.68 ± 1.36 years; interquartile range, 56.22-59.14 years; 58.9% male; 41.1% female). Genotypes 1a and 1b accounted for 75.7% of cases and the prevalent therapeutic regimen was sofosbuvir/simeprevir. Sustained viral response accounted for 98.9% and the METAVIR score F3/F4 for 50.8%. Increased alanine transferase was significantly correlated with an increase in α-fetoproteins (

Indexed as

comorbiditiesdepressiongastrointestinalincidencesustained virological response

Identifiers

PMID33066136
PMCPMC7601958
OpenAlexW3092768545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.