Evidence map›Paper›PMID 33066115›Full record

ArticleMicroorganisms2020

Impact of Yeast-Derived β-Glucans on the Porcine Gut Microbiota and Immune System in Early Life.

Hugo de Vries, Mirelle Geervliet, Christine A Jansen, Victor P M G Rutten, Hubèrt van Hees, Natalie Groothuis, Jerry M Wells, Huub F J Savelkoul, Edwin Tijhaar, Hauke Smidt

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  9. Review
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  13. Feeding coproducts to pigs to reduce feed cost and reach sustainable food production.Animal frontiers : the review magazine of animal agriculture · 2022
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  18. Effects ofFrontiers in microbiology · 2022
    Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Hugo de VriesLaboratory of Microbiology, Wageningen University, 6700 EH Wageningen, The Netherlands.ORCID 0000-0002-8888-7202
Mirelle GeervlietCell Biology and Immunology Group, Wageningen University, 6700 AH Wageningen, The Netherlands.ORCID 0000-0001-8011-4144
Christine A JansenDepartment of Biomolecular Health Sciences, Division of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.ORCID 0000-0003-0740-0835
Victor P M G RuttenDepartment of Biomolecular Health Sciences, Division of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.ORCID 0000-0002-6171-1805
Hubèrt van HeesResearch and Development, Trouw Nutrition, 3800 AG Amersfoort, The Netherlands.ORCID 0000-0002-1457-1731
Natalie GroothuisCell Biology and Immunology Group, Wageningen University, 6700 AH Wageningen, The Netherlands.
Jerry M WellsHost-Microbe Interactomics Group, Wageningen University, 6700 AH Wageningen, The Netherlands.
Huub F J SavelkoulCell Biology and Immunology Group, Wageningen University, 6700 AH Wageningen, The Netherlands.ORCID 0000-0001-6236-7092
Edwin TijhaarCell Biology and Immunology Group, Wageningen University, 6700 AH Wageningen, The Netherlands.ORCID 0000-0002-9014-0407
Hauke SmidtLaboratory of Microbiology, Wageningen University, 6700 EH Wageningen, The Netherlands.ORCID 0000-0002-6138-5026
Wageningen University & Research · NLUtrecht University · NL

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 868.15.032Vereniging Diervoeders Nederland (VDN) 868.15.032
6 · The paper itself

Abstract

Piglets are susceptible to infections in early life and around weaning due to rapid environmental and dietary changes. A compelling target to improve pig health in early life is diet, as it constitutes a pivotal determinant of gut microbial colonization and maturation of the host's immune system. In the present study, we investigated how supplementation of yeast-derived β-glucans affects the gut microbiota and immune function pre- and post-weaning, and how these complex systems develop over time. From day two after birth until two weeks after weaning, piglets received yeast-derived β-glucans or a control treatment orally and were subsequently vaccinated against

Indexed as

early lifegastro-intestinal tractgut microbiotaimmune systemporcineβ-glucans

Identifiers

PMID33066115
PMCPMC7601942
OpenAlexW3092847361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.