Evidence map›Paper›PMID 33065811›Full record

SynthesisJournal of affective disorders2020

Prevalence of perinatal depression and its determinants in Mainland China: A systematic review and meta-analysis.

Anum Nisar, Juan Yin, Ahmed Waqas, Xue Bai, Duolao Wang, Atif Rahman, Xiaomei Li

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07639099 (Impact of Intranasal Esketamine-dexmedetomidine Combination on Postpartum Depression in Parturients With Prenatal Depressive Symptoms), which is not on this map. Cited by 169 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed, 10 pooled it
24.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07639099 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Intranasal Esketamine-dexmedetomidine Combination on Postpartum Depression in Parturients With Prenatal Depressive Symptoms: a Randomized, Double-blind, and Placebo-controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2026 to 2029Enrolled164ConditionsParturients, Depressive Symptoms, Esketamine, DexmedetomidineArmsEsketamine-dexmedetomidine combination, Placebo
3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 10 syntheses or guidelines pooled it, 327 citations in OpenAlex.

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109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Anum NisarXi'an Jiaotong University, Xi'an, China.
Juan YinXi'an Jiaotong University, Xi'an, China.
Ahmed WaqasUniversity of Liverpool, Liverpool, United Kingdom; Human Development Research Foundation, Islamabad, Pakistan.
Xue BaiXi'an Jiaotong University, Xi'an, China.
Duolao WangLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Atif RahmanUniversity of Liverpool, Liverpool, United Kingdom.
Xiaomei LiXi'an Jiaotong University, Xi'an, China. Electronic address: roselee@xjtu.edu.cn.
Xi'an Jiaotong University · CNUniversity of Liverpool · GBLiverpool School of Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerinatal depression is a maternal mental health condition that is associated with various adverse health outcomes both for the mothers and the babies. The study aim was to estimate the prevalence of perinatal depression and its risks and determinants in Mainland China.

methodsSystematic searches were conducted in 10 major databases and random effect meta-analysis was performed to achieve the pooled variance of perinatal depression. Subgroup analyses were conducted based on region, scale, methods of diagnosis and study design. Meta-regression was performed with the variables such as age, quality assessment score and gross domestic product (GDP) of the province.

resultsPooled prevalence of perinatal depression was 16.3% (CI=95%; 14.7% to 18.2%, P < 0.001), with antenatal depression 19.7% (CI=95%; 15.8% to 24.2%, P < 0.001) and postnatal depression 14.8% (CI=95%; 13.1% to 16.6%, P < 0.001). Significant publication bias was found and heterogeneity was I LIMITATIONS: The review does not include studies with small sample size (n <250). Moreover a narrative review of risk and protective factors was done, these were not included in meta-analysis.

conclusionThe prevalence of perinatal depression in China is similar to low and middle-income countries. Urgent attention is needed to address this public health priority in China.

Indexed as

Depression, PostpartumDepressive DisorderChinaDepressionFemaleHumansPregnancyPrevalenceChinaMaternal mental healthPerinatal depressionPrevalenceRisk factors

Identifiers

PMID33065811
OpenAlexW3043668422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.