Evidence map›Paper›PMID 33065559›Full record

ArticlePhysics in medicine and biology2020

Noise reduction in CT image using prior knowledge aware iterative denoising.

Shengzhen Tao, Kishore Rajendran, Wei Zhou, Joel G Fletcher, Cynthia H McCollough, Shuai Leng

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. ErisNet: A Deep Learning Model for Noise Reduction in CT Images.Bioengineering (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Journal of medical imaging (Bellingham, Wash.) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shengzhen Tao4500 San Pablo Rd, Jacksonville, FL, 32224, United States of America.ORCID 0000-0003-3019-3491
Kishore RajendranDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, United States of America.ORCID 0000-0002-8314-3642
Wei ZhouDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, United States of America.
Joel G FletcherDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, United States of America.
Cynthia H McColloughDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, United States of America.
Shuai LengDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, United States of America.
Mayo Clinic · US

Funding

Photon-Counting Spectral CT to Reduce Dose and Detect Early Vascular DiseaseR01EB016966 · NIBIB · MAYO CLINIC ROCHESTER · PI MCCOLLOUGH, CYNTHIA H · 2013 to 2017
$5.1M
Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
EXTRAMURAL RES FACIL IMPROVEMENT PROG: POLYCYSTIC KIDNEY DISEASE, RENAL STUDIES,C06RR018898 · NCRR · MAYO CLINIC · PI BURNETT, JOHN C · 2004 to 2004
$2.3M
NCRR NIH HHS C06 RR018898NIBIB NIH HHS R01 EB016966NIBIB NIH HHS R01 EB028590
6 · The paper itself

Abstract

The clinical demand for low image noise often limits the slice thickness used in many CT applications. However, a thick-slice image is more susceptible to longitudinal partial volume effects, which can blur key anatomic structures and pathologies of interest. In this work, we develop a prior knowledge aware iterative denoising (PKAID) framework that utilizes spatial data redundancy in the slice increment direction to generate low-noise, thin-slice images, and demonstrate its application in non-contrast head CT exams. The proposed technique takes advantage of the low noise of thicker images and exploits the structural similarity between the thick- and thin-slice images to reduce noise in the thin-slice image. Phantom data and patient cases (

Indexed as

AlgorithmsTomography, X-Ray ComputedHeadHumansPhantoms, ImagingRadiation DosageSignal-To-Noise Ratiocomputed tomographydenoisinghead CTnoise reductionslice thickness

Identifiers

PMID33065559
PMCPMC8050138
OpenAlexW3092705909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.