Evidence map›Paper›PMID 33065371›Full record

ReviewCurrent opinion in microbiology2020

The RESTRICTION checkpoint: a window of opportunity governing developmental transitions in Toxoplasma gondii.

Anthony P Sinai, Elena S Suvorova

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. The Centrocone Protein SMC_N1 Is Important for the Proliferation ofAnimals : an open access journal from MDPI · 2026
    Article
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  6. Review
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  10. The Modular Circuitry of Apicomplexan Cell Division Plasticity.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anthony P SinaiDepartment of Microbiology Immunology and Molecular Genetics, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536, USA.
Elena S SuvorovaDepartment of Internal Medicine, Division of Infectious Diseases and International Medicine, Morsani College of Medicine, University of South Florida, 3720 Spectrum Blvd, Tampa, FL 33612, USA. Electronic address: suvorova@usf.edu.
University of Kentucky · USUniversity of South Florida · US

Funding

Cyclin-mediated control of Toxoplasma developmentR01AI141467 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SUVOROVA, ELENA · 2020 to 2024
$1.9M
Quantitative Approaches for Drug Testing in Chronic Toxoplasmosis: Leveraging New Insights Into Bradyzoite Biology Within Tissue Cysts In VivoR01AI145335 · NIAID · UNIVERSITY OF KENTUCKY · PI PATWARDHAN, ABHIJIT R., SINAI, ANTHONY P. · 2019 to 2021
$1.1M
NIAID NIH HHS R01 AI141467NIAID NIH HHS R01 AI145335
6 · The paper itself

Abstract

The life cycle of Toxoplasma gondii is characterized by active replication alternating with periods of rest. Encysted dormant sporozoites and bradyzoites initiate active replication as tachyzoites and merozoites. Here we explore the role of the cell cycle with a focus on the canonical G

Indexed as

Cell Cycle CheckpointsAnimalsHumansLife Cycle StagesToxoplasmaToxoplasmosis

Identifiers

PMID33065371
PMCPMC8019522
OpenAlexW3092987933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.