Evidence map›Paper›PMID 33065104›Full record

ArticleChest2021

Ansa Cervicalis Stimulation: A New Direction in Neurostimulation for OSA.

David T Kent, David Zealear, Alan R Schwartz

Open access · greenAbstract read
In one paragraph

Article in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Intraoperative Identification and Stimulation of the Ansa Cervicalis Nerve Plexus.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  5. Observational
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Objective Pharyngeal Phenotyping in Obstructive Sleep Apnea With High-Resolution Manometry.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023
    Article
  17. Quantitative Effects of Ansa Cervicalis Stimulation in Obstructive Sleep Apnea.American journal of respiratory and critical care medicine · 2023
    Article
  18. Review
  19. Obstructive sleep apnea.Handbook of clinical neurology · 2022
    Review
  20. Hypoglossal Nerve Stimulation Therapy.Advances in experimental medicine and biology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

David T KentDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN. Electronic address: david.kent@vumc.org.
David ZealearDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN.
Alan R SchwartzDepartment of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Universidad Peruana Cayetano Heredia School of Medicine, Lima, Peru.
Vanderbilt University Medical Center · USUniversity of Pennsylvania · US

Funding

Lingual muscle control of upper airway patency in obstructive sleep apneaR01HL144859 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DEDHIA, RAJ C., SCHWARTZ, ALAN R. · 2019 to 2023
$3.9M
The Effect of Ansa Cervicalis Neurostimulation on Airway Patency in Obstructive Sleep ApneaR01HL161635 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David T. Kent · 2022 to 2026
$3.9M
NHLBI NIH HHS R01 HL144859NHLBI NIH HHS R01 HL161635
6 · The paper itself

Abstract

backgroundHypoglossal nerve stimulation (HNS) is an alternative treatment option for patients with OSA unable to tolerate positive airway pressure but implant criteria limit treatment candidacy. Previous research indicates that caudal tracheal traction plays an important role in stabilizing upper airway patency. RESEARCH QUESTION: Does contraction of the sternothyroid muscle with ansa cervicalis stimulation (ACS), which pulls the pharynx caudally via thyroid cartilage insertions, increase maximum inspiratory airflow (V STUDY DESIGN AND

methodsHook-wire percutaneous electrodes were used to stimulate the medial branch of the right hypoglossal nerve and right branch of the ansa cervicalis innervating the sternothyroid muscle during propofol sedation. V

resultsEight participants with OSA were studied using ACS with and without HNS. Compared with baseline, the mean V

interpretationACS independently increased V

Indexed as

PharynxSleep Apnea, ObstructiveEndoscopyFemaleHumansHypoglossal NerveMaleMiddle AgedNeck MusclesResearch DesignRespiratory MechanicsRespiratory Physiological PhenomenaTracheaTranscutaneous Electric Nerve Stimulationansa cervicalishypoglossal nerve stimulationOSAsternothyroid muscletracheal traction

Identifiers

PMID33065104
PMCPMC8097630
OpenAlexW3117979244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.