SynthesisEuropean journal of pain (London, England)2021
Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines.
Synthesis in European journal of pain (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 233 papers, 17 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development of a Tele-Physiotherapy Tool for the Early Management of Muskuloskeletal Pain in People With Visual Impairement (TeleEDxPhysio)
The METRIC Study Protocol: an Explanatory Randomized Controlled Trial Investigating the Neurophysiological Mechanisms Underlying the Therapeutic Effects of Spinal Manipulative Therapy for Chronic Primary Low Back Pain
Comparison Between Pragmatically Applied Orthopedic Manual Therapy and Dry Needling for Low Back Pain.
Effects of Percutaneous Peripheral Nerve Stimulation on Neck and Low Back Pain: a Quadruple-blinded, Randomized Clinical Trial
Comparison of Electrical Dry Needling and Therapeutic Exercise Versus Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial
Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial
Comparison of Telemedicine and Conventional Monitoring Methods in Nonspecific Neck Pain
Possible Mechanisms of Action of Magnetic Tape Through Its Application on the Epidermis
Who cites it
233 citing papers in PubMed, 17 syntheses or guidelines pooled it, 469 citations in OpenAlex.
- The effects of physiotherapy on neck pain with associated symptoms, ıncludıng cervicogenic dizziness and tinnitus: a systematic review.BMC musculoskeletal disorders · 2026Pooled it
- Effectiveness of telerehabilitation exercises in low back pain: a systematic review.Irish journal of medical science · 2025Pooled it
- Exercise Therapy Versus Manual Therapy for the Management of Pain Intensity, Disability, and Physical Function in People With Chronic Low Back Pain: A Systematic Review With Meta-Analysis and Meta-Regression.European journal of pain (London, England) · 2025Pooled it
- Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain.Chiropractic & manual therapies · 2025Pooled it
- Management of patients with cancer pain: an evaluation of AGREE II-based clinical practice guidelines.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Structural and Psychometric Properties of Neck Pain Questionnaires Through Patient-Reported Outcome Measures: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The Efficacy of Virtual Reality on the Rehabilitation of Musculoskeletal Diseases: Umbrella Review.Journal of medical Internet research · 2025Pooled it
- Effectiveness and adverse effects of immersive technologies used for rehabilitation of patients with non-specific neck pain: a systematic review.Journal of rehabilitation medicine · 2025Pooled it
- Quality appraisal of clinical practice guidelines for attention deficit hyperactivity disorder: a systematic review using the appraisal of guidelines for research and evaluation (AGREE II) instrument.Frontiers in psychiatry · 2025Pooled it
- The Effectiveness of Video Animations as a Tool to Improve Health Information Recall for Patients: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Therapeutic effects of different acupuncture methods on chronic nonspecific low back pain: A network meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Adverse events in India's Ayush interventions for cervical and lumbar spondylosis: a systematic review.European journal of medical research · 2024Pooled it
- Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A 'trustworthy' systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2024Pooled it
- Efficacy of neuromobilization in the treatment of low back pain: Systematic review and meta-analysis.PloS one · 2024Pooled it
- Clinical efficacy of acupuncture therapy combined with core muscle exercises in treating patients with chronic nonspecific low back pain: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2024Pooled it
- Summarizing the effects of different exercise types in chronic neck pain - a systematic review and meta-analysis of systematic reviews.BMC musculoskeletal disorders · 2023Pooled it
- Is the combination of exercise therapy and health education more effective than usual medical care in the prevention of non-specific back pain? A systematic review with meta-analysis.Annals of medicine · 2022Pooled it
- Cost-effectiveness of Pilates compared with home-based exercises for people with chronic non-specific low back pain: a trial-based economic evaluation.BMC musculoskeletal disorders · 2026Trial
- Short-term effects of diaphragmatic myofascial release on pain, mobility, and disability in chronic nonspecific low back pain: a randomized sham-controlled trial.Scientific reports · 2026Trial
- Efficacy and cortical mechanisms of repetitive peripheral magnetic stimulation in non-specific neck and low back pain: a prospective, two-center, randomized, sham-controlled fNIRS study.Journal of translational medicine · 2026Trial
173 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveThis systematic review synthesized evidence from European neck and low back pain (NLBP) clinical practice guidelines (CPGs) to identify recommended treatment options for use across Europe. DATABASES AND DATA TREATMENT: Comprehensive searches of thirteen databases were conducted, from 1st January 2013 to 4th May 2020 to identify up-to-date evidence-based European CPGs for primary care management of NLBP, issued by professional bodies/organizations. Data extracted included; aim and target population, methods for development and implementation and treatment recommendations. The AGREE II checklist was used to critically appraise guidelines. Criteria were devised to summarize and synthesize the direction and strength of recommendations across guidelines.
resultsSeventeen CPGs (11 low back; 5 neck; 1 both) from eight European countries were identified, of which seven were high quality. For neck pain, there were consistent weak or moderate strength recommendations for: reassurance, advice and education, manual therapy, referral for exercise therapy/programme, oral analgesics and topical medications, plus psychological therapies or multidisciplinary treatment for specific subgroups. Notable recommendation differences between back and neck pain included, i) analgesics for neck pain (not for back pain); ii) options for back pain-specific subgroups-work-based interventions, return to work advice/programmes and surgical interventions (but not for neck pain) and iii) a greater strength of recommendations (generally moderate or strong) for back pain than those for neck pain.
conclusionsThis review of European CPGs identified a range of mainly non-pharmacological recommended treatment options for NLBP that have broad consensus for use across Europe. SIGNIFICANCE: Consensus regarding evidence-based treatment recommendations for patients with neck and low back pain (NLBP) from recent European clinical practice guidelines identifies a wide range of predominantly non-pharmacological treatment options. This includes options potentially applicable to all patients with NLBP and those applicable to only specific patient subgroups. Future work within our Back-UP research team will transfer these evidence-based treatment options to an accessible clinician decision support tool for first contact clinicians.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.