Evidence map›Paper›PMID 33064878›Full record

SynthesisEuropean journal of pain (London, England)2021

Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines.

Nadia Corp, Gemma Mansell, Siobhán Stynes, Gwenllian Wynne-Jones, Lars Morsø, Jonathan C Hill, Danielle A van der Windt

8 registry-linked trialsOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in European journal of pain (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 233 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed, 17 pooled it
33.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05478200 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Development of a Tele-Physiotherapy Tool for the Early Management of Muskuloskeletal Pain in People With Visual Impairement (TeleEDxPhysio)

TypeinterventionalSponsorEscuela Universitaria de Fisioterapia de la OnceRan2022 to 2024Enrolled128ConditionsLow Back Pain, Visual ImpairmentArmsphysical exercise, Manual therapy
NCT05986370 narecruitingnot on this mapstarted 2023, after this paper: background citation

The METRIC Study Protocol: an Explanatory Randomized Controlled Trial Investigating the Neurophysiological Mechanisms Underlying the Therapeutic Effects of Spinal Manipulative Therapy for Chronic Primary Low Back Pain

TypeinterventionalSponsorUniversité du Québec à Trois-RivièresRan2023 to 2026Enrolled112ConditionsChronic Low-back PainArmslumbar spinal manipulative therapy, sham spinal manipulative therapy, full spine spinal manipulative therapy
NCT06150625 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparison Between Pragmatically Applied Orthopedic Manual Therapy and Dry Needling for Low Back Pain.

TypeinterventionalSponsorYoungstown State UniversityRan2023 to 2025Enrolled188ConditionsLow Back Pain, MechanicalArmsOrthopedic Manaual Therapy, Dry Needling, Home exercise program, Patient education
NCT06153875 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Percutaneous Peripheral Nerve Stimulation on Neck and Low Back Pain: a Quadruple-blinded, Randomized Clinical Trial

TypeinterventionalSponsorClinica Francisco Ortega Rehabilitacion Avanzada SLRan2023 to 2024Enrolled45ConditionsNeck Pain, Low Back PainArmsSensory Thresold, Burst High Frecuency, Theta-Burst Stimulation, Transcutaneous Electrical Nerve Stimulation
NCT06522893 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Electrical Dry Needling and Therapeutic Exercise Versus Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AlmeriaRan2025 to 2026Enrolled90ConditionsNeck Pain, Chronic PainArmsElectrical Dry Needling and Therapeutic exercise, Therapeutic exercise
NCT06695949 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AlmeriaRan2025 to 2025Enrolled100ConditionsNeck Pain, Chronic PainArmsPercutaneous neuromodulation., Therapeutic Exercise.
NCT06818422 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Telemedicine and Conventional Monitoring Methods in Nonspecific Neck Pain

TypeinterventionalSponsorAntalya Training and Research HospitalRan2025 to 2025Enrolled68ConditionsNeck Pain, Exercise, TelemedicineArmsHome exercise and recommendations for nonspecific neck pain
NCT07034456 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Possible Mechanisms of Action of Magnetic Tape Through Its Application on the Epidermis

TypeinterventionalSponsorPatricia Beltra LopezRan2025 to 2026Enrolled30ConditionsHealthy VolunteersArmsTape with mangetic particles, Topical Anesthetic Cream, Control KinesioTape, Moisturizing Cream (control)
3 · Its place in the literature

Who cites it

233 citing papers in PubMed, 17 syntheses or guidelines pooled it, 469 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Management of patients with cancer pain: an evaluation of AGREE II-based clinical practice guidelines.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Pooled it
  17. Pooled it
  18. Trial
  19. Trial
  20. Trial

173 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nadia CorpPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Gemma MansellPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Siobhán StynesPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Gwenllian Wynne-JonesPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Lars MorsøOpen Patient data Explorative Network, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Jonathan C HillPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Danielle A van der WindtPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, UK.
Aston University · GBUniversity of Southern Denmark · DKArthritis UK · GBMidlands Partnership NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveThis systematic review synthesized evidence from European neck and low back pain (NLBP) clinical practice guidelines (CPGs) to identify recommended treatment options for use across Europe. DATABASES AND DATA TREATMENT: Comprehensive searches of thirteen databases were conducted, from 1st January 2013 to 4th May 2020 to identify up-to-date evidence-based European CPGs for primary care management of NLBP, issued by professional bodies/organizations. Data extracted included; aim and target population, methods for development and implementation and treatment recommendations. The AGREE II checklist was used to critically appraise guidelines. Criteria were devised to summarize and synthesize the direction and strength of recommendations across guidelines.

resultsSeventeen CPGs (11 low back; 5 neck; 1 both) from eight European countries were identified, of which seven were high quality. For neck pain, there were consistent weak or moderate strength recommendations for: reassurance, advice and education, manual therapy, referral for exercise therapy/programme, oral analgesics and topical medications, plus psychological therapies or multidisciplinary treatment for specific subgroups. Notable recommendation differences between back and neck pain included, i) analgesics for neck pain (not for back pain); ii) options for back pain-specific subgroups-work-based interventions, return to work advice/programmes and surgical interventions (but not for neck pain) and iii) a greater strength of recommendations (generally moderate or strong) for back pain than those for neck pain.

conclusionsThis review of European CPGs identified a range of mainly non-pharmacological recommended treatment options for NLBP that have broad consensus for use across Europe. SIGNIFICANCE: Consensus regarding evidence-based treatment recommendations for patients with neck and low back pain (NLBP) from recent European clinical practice guidelines identifies a wide range of predominantly non-pharmacological treatment options. This includes options potentially applicable to all patients with NLBP and those applicable to only specific patient subgroups. Future work within our Back-UP research team will transfer these evidence-based treatment options to an accessible clinician decision support tool for first contact clinicians.

Indexed as

Low Back PainAnalgesicsEuropeExercise TherapyGuidelines as TopicHumansNeck PainAnalgesics

Identifiers

PMID33064878
PMCPMC7839780
OpenAlexW3092812279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.