ReviewClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2021
The role of nasal congestion as a defence against respiratory viruses.
Review in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Generation of apical-out nasal organoids to facilitate human respiratory syncytial virus infection and drug screening.iScience · 2026Article
- Intraperitoneal versus intranasal administration of lipopolysaccharide in causing sepsis severity in a murine model: a preliminary comparison.Laboratory animal research · 2024Article
- Temperature influences commensal-pathogen dynamics in a nasal epithelial cell co-culture model.mSphere · 2024Article
- Nasal turbinate lymphatic obstruction: a proposed new paradigm in the etiology of essential hypertension.Frontiers in medicine · 2024Article
- Nasal lymphatic obstruction of CSF drainage as a possible cause of Alzheimer's disease and dementia.Frontiers in aging neuroscience · 2024Article
- A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study.Journal of clinical medicine · 2023Article
- Detection of canine obstructive nasal disease using infrared thermography: A pilot study.PloS one · 2023Article
- Intracranially Extended Sinonasal Undifferentiated Carcinoma: A Case Report and Literature Review.The American journal of case reports · 2022Review
- The role of nasal congestion as a defence against respiratory viruses.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis review discusses how nasal congestion may have benefits as a mechanism of defence against respiratory viruses.
methodsA literature research was conducted on respiratory viruses and nasal congestion, following a recently published review on how temperature sensitivity is important for the success of common respiratory viruses.
resultsThe literature reported that common respiratory viruses are temperature sensitive and replicate well at the cooler temperatures of the upper airways (32°C), but replication is restricted at body temperature (37°C). The amplitude of the phases of congestion and decongestion associated with the nasal cycle was increased on infection with respiratory viruses and this caused unilateral nasal congestion and obstruction. Nasal congestion and obstruction increase nasal mucosal temperature towards 37°C and therefore restricted the replication of respiratory viruses.
conclusionNasal congestion associated with the nasal cycle may act as a mechanism of respiratory defence against infection with respiratory viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.