Evidence map›Paper›PMID 33064272›Full record

ArticleJournal of gastrointestinal cancer2021

Prognostic and Predictive Value of NAR Score in Gastric Cancer.

Gokhan Ucar, Yusuf Acikgoz, Yakup Ergun, Tulay Eren, Merve Dirikoc, Selin Aktürk Esen, Ozan Yazıcı, Dogan Uncu, Nuriye Yildirim Ozdemir

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Article in Journal of gastrointestinal cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Gokhan UcarMedical Oncology, Ankara City Hospital, Ankara, Turkey. gokhanucar_1@hotmail.com.ORCID https://orcid.org/0000-0002-7649-1075
Yusuf AcikgozMedical Oncology, Ankara City Hospital, Ankara, Turkey.
Yakup ErgunMedical Oncology, Ankara City Hospital, Ankara, Turkey.
Tulay ErenMedical Oncology, Yıldırım Beyazıt Dışkapı Training and Research Hospital, Ankara, Turkey.
Merve DirikocMedical Oncology, Ankara City Hospital, Ankara, Turkey.
Selin Aktürk EsenMedical Oncology, Ankara City Hospital, Ankara, Turkey.
Ozan YazıcıMedical Oncology, Medicine Faculty of Gazi University, Ankara, Turkey.
Dogan UncuMedical Oncology, Ankara City Hospital, Ankara, Turkey.
Nuriye Yildirim OzdemirMedical Oncology, Medicine Faculty of Gazi University, Ankara, Turkey.
Memorial Ankara Hospital · TRGazi University · TRDışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeoadjuvant treatment is a widely accepted approach for locally advanced rectum cancer. Efforts to explore a surrogate endpoint for clinical trials revealed a new prognostic scoring system which is named as neoadjuvant rectal score (NAR) in patients who received neoadjuvant treatment for rectal cancer. MATERIAL AND

methods88 patients who met inclusion criteria were included in the study. The optimal cutoff value of the NAR score was 17.6 with 71% sensitivity and 63% specificity. Patients with NAR score > 17.6 (n: 48, 54%) were defined as the high-risk group and those with NAR score ≤ 17.6 (n: 40, 56%) as the low-risk group.

resultSurvival analysis according to the NAR score group (low-risk vs high-risk) revealed that there was a statistically significant difference between groups regarding OS and DFS. The median OS for high-risk patients was 27.3 months (95% CI, 15.0-39.6); it was 76.6 months (47.3-106.0) for low-risk patients (p < 0.0001). The median DFS was 15.1 months (11.8-18.4) for high-risk patients; it was 44.3 months (95% CI, 4.1-84.6) in the low-risk group (p = 0.002). DISCUSSION: As a result, we interpreted our findings as supporting data about the utility of NAR score not only as a surrogate endpoint for the clinical trial of rectal cancer but also as a prognostic marker in patients with gastric cancer who received neoadjuvant treatment.

Indexed as

PrognosisAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoadjuvant TherapyPredictive Value of TestsRectal NeoplasmsRisk AssessmentROC CurveStomach NeoplasmsTurkeyGastric cancerNAR scoreNeoadjuvantPredictivePrognostic

Identifiers

PMID33064272
OpenAlexW3092740001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.